KEGG

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 Including 64 KEGG pathways in ASD, 26 in ID, 17 in EE and 34 in SCZ.
   KEGG pathway
KEGG accession KEGG pathway name Number of reference genes Number of genes Expected number Ratio of entrichment Raw P_Value Adjusted P_Value Genes related Other disease
04810 Regulation of actin cytoskeleton 213 13 1.63 7.98 1.27e-08 1.23e-06 SCZ
04510 Focal adhesion 200 12 1.53 7.84 5.59e-08 2.71e-06 EE SCZ
04972 Pancreatic secretion 101 8 0.77 10.35 1.18e-06 3.82e-05 EE
04971 Gastric acid secretion 74 7 0.57 12.36 1.67e-06 4.05e-05 SCZ
04270 Vascular smooth muscle contraction 116 8 0.89 9.01 3.35e-06 6.50e-05 SCZ
04970 Salivary secretion 89 7 0.68 10.28 5.80e-06 6.75e-05 EE SCZ
05010 Alzheimer's disease 167 9 1.28 7.04 6.26e-06 6.75e-05 ID
05414 Dilated cardiomyopathy 90 7 0.69 10.16 6.25e-06 6.75e-05 EE SCZ
04512 ECM-receptor interaction 85 7 0.65 10.76 4.27e-06 6.75e-05 SCZ
04020 Calcium signaling pathway 177 9 1.35 6.65 1.00e-05 9.70e-05 EE SCZ
04912 GnRH signaling pathway 101 7 0.77 9.06 1.34e-05 0.0001 ID SCZ
04070 Phosphatidylinositol signaling system 78 6 0.60 10.05 3.10e-05 0.0002 -
05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 74 6 0.57 10.60 2.29e-05 0.0002 ID SCZ
04540 Gap junction 90 6 0.69 8.71 6.96e-05 0.0005 SCZ
04145 Phagosome 153 7 1.17 5.98 0.0002 0.0012 -
04010 MAPK signaling pathway 268 9 2.05 4.39 0.0002 0.0012 -
04360 Axon guidance 129 6 0.99 6.08 0.0005 0.0023 -
04973 Carbohydrate digestion and absorption 44 4 0.34 11.88 0.0004 0.0023 -
05222 Small cell lung cancer 85 5 0.65 7.69 0.0005 0.0023 EE
05410 Hypertrophic cardiomyopathy (HCM) 83 5 0.64 7.87 0.0005 0.0023 EE
04330 Notch signaling pathway 47 4 0.36 11.12 0.0005 0.0023 -
04530 Tight junction 132 6 1.01 5.94 0.0006 0.0026 ID SCZ
04310 Wnt signaling pathway 150 6 1.15 5.23 0.0011 0.0046 -
05146 Amoebiasis 106 5 0.81 6.16 0.0014 0.0057 EE SCZ
04114 Oocyte meiosis 112 5 0.86 5.83 0.0018 0.0070 ID
04115 p53 signaling pathway 68 4 0.52 7.69 0.0019 0.0071 -
04720 Long-term potentiation 70 4 0.54 7.47 0.0021 0.0075 EE ID SCZ
04976 Bile secretion 71 4 0.54 7.36 0.0022 0.0076 SCZ
05016 Huntington's disease 183 6 1.40 4.28 0.0030 0.0100 ID
05322 Systemic lupus erythematosus 136 5 1.04 4.80 0.0041 0.0128 -
04960 Aldosterone-regulated sodium reabsorption 42 3 0.32 9.33 0.0041 0.0128 -
04914 Progesterone-mediated oocyte maturation 86 4 0.66 6.08 0.0044 0.0133 SCZ
05215 Prostate cancer 89 4 0.68 5.87 0.0049 0.0144 EE ID
04930 Type II diabetes mellitus 48 3 0.37 8.17 0.0060 0.0171 EE
05213 Endometrial cancer 52 3 0.40 7.54 0.0074 0.0199 -
04916 Melanogenesis 101 4 0.77 5.18 0.0077 0.0199 ID
04150 mTOR signaling pathway 52 3 0.40 7.54 0.0074 0.0199 -
05014 Amyotrophic lateral sclerosis (ALS) 53 3 0.41 7.40 0.0078 0.0199 EE ID
05142 Chagas disease (American trypanosomiasis) 104 4 0.80 5.03 0.0085 0.0211 -
05130 Pathogenic Escherichia coli infection 56 3 0.43 7.00 0.0091 0.0221 ID
04660 T cell receptor signaling pathway 108 4 0.83 4.84 0.0097 0.0229 -
05131 Shigellosis 61 3 0.47 6.43 0.0115 0.0266 -
04670 Leukocyte transendothelial migration 116 4 0.89 4.51 0.0123 0.0277 SCZ
05200 Pathways in cancer 326 7 2.49 2.81 0.0133 0.0293 SCZ
05214 Glioma 65 3 0.50 6.03 0.0137 0.0295 EE ID
04320 Dorso-ventral axis formation 24 2 0.18 10.89 0.0144 0.0297 -
01100 Metabolic pathways 1130 16 8.65 1.85 0.0143 0.0297 ID SCZ
00601 Glycosphingolipid biosynthesis - lacto and neolacto series 26 2 0.20 10.05 0.0168 0.0323 -
03018 RNA degradation 71 3 0.54 5.52 0.0173 0.0323 -
04722 Neurotrophin signaling pathway 127 4 0.97 4.12 0.0167 0.0323 ID
04730 Long-term depression 70 3 0.54 5.60 0.0167 0.0323 EE SCZ
05218 Melanoma 71 3 0.54 5.52 0.0173 0.0323 -
05145 Toxoplasmosis 132 4 1.01 3.96 0.0189 0.0340 SCZ
04080 Neuroactive ligand-receptor interaction 272 6 2.08 2.88 0.0189 0.0340 EE ID
04514 Cell adhesion molecules (CAMs) 133 4 1.02 3.93 0.0194 0.0342 SCZ
04370 VEGF signaling pathway 76 3 0.58 5.16 0.0207 0.0359 -
04260 Cardiac muscle contraction 77 3 0.59 5.09 0.0214 0.0364 EE
00020 Citrate cycle (TCA cycle) 30 2 0.23 8.71 0.0221 0.0370 -
04664 Fc epsilon RI signaling pathway 79 3 0.60 4.96 0.0229 0.0376 -
00640 Propanoate metabolism 32 2 0.24 8.17 0.0249 0.0403 -
04350 TGF-beta signaling pathway 84 3 0.64 4.67 0.0268 0.0426 ID
04012 ErbB signaling pathway 87 3 0.67 4.51 0.0294 0.0460 -
00565 Ether lipid metabolism 36 2 0.28 7.26 0.0310 0.0477 -