Including 38 wikipathways in ASD, 22 in ID, 20 in EE and 39 in SCZ. |
wiki accession | wiki pathway name | Number of reference genes | Number of genes | Expected number | Ratio of entrichment | Raw P_Value | Adjusted P_Value | Genes related | Other disease |
---|---|---|---|---|---|---|---|---|---|
DB_ID:1637 | Proteoglycan syndecan-mediated signaling events | 1345 | 37 | 10.29 | 3.60 | 2.43e-11 | 7.44e-09 | ID SCZ | |
DB_ID:1499 | Integrin family cell surface interactions | 1378 | 36 | 10.54 | 3.41 | 1.89e-10 | 2.89e-08 | ID SCZ | |
DB_ID:1517 | Beta1 integrin cell surface interactions | 1351 | 35 | 10.34 | 3.39 | 4.30e-10 | 4.39e-08 | ID SCZ | |
DB_ID:1619 | Endothelins | 1307 | 34 | 10.00 | 3.40 | 6.99e-10 | 5.35e-08 | ID SCZ | |
DB_ID:1472 | Nectin adhesion pathway | 1295 | 33 | 9.91 | 3.33 | 2.11e-09 | 6.34e-08 | ID SCZ | |
DB_ID:1556 | Plasma membrane estrogen receptor signaling | 1301 | 33 | 9.96 | 3.31 | 2.36e-09 | 6.34e-08 | ID SCZ | |
DB_ID:1516 | Signaling events mediated by VEGFR1 and VEGFR2 | 1296 | 33 | 9.92 | 3.33 | 2.15e-09 | 6.34e-08 | ID SCZ | |
DB_ID:1635 | Sphingosine 1-phosphate (S1P) pathway | 1311 | 33 | 10.03 | 3.29 | 2.84e-09 | 6.34e-08 | ID SCZ | |
DB_ID:143 | Neuronal System | 188 | 13 | 1.44 | 9.04 | 2.83e-09 | 6.34e-08 | EE ID SCZ | |
DB_ID:1575 | VEGF and VEGFR signaling network | 1304 | 33 | 9.98 | 3.31 | 2.50e-09 | 6.34e-08 | ID SCZ | |
DB_ID:1480 | TRAIL signaling pathway | 1328 | 34 | 10.16 | 3.35 | 1.05e-09 | 6.34e-08 | ID SCZ | |
DB_ID:1454 | Syndecan-1-mediated signaling events | 1300 | 33 | 9.95 | 3.32 | 2.31e-09 | 6.34e-08 | ID SCZ | |
DB_ID:1573 | ErbB receptor signaling network | 1312 | 33 | 10.04 | 3.29 | 2.90e-09 | 6.34e-08 | ID SCZ | |
DB_ID:1578 | Alpha9 beta1 integrin signaling events | 1305 | 33 | 9.99 | 3.30 | 2.54e-09 | 6.34e-08 | ID SCZ | |
DB_ID:1509 | Internalization of ErbB1 | 1288 | 32 | 9.86 | 3.25 | 6.83e-09 | 6.50e-08 | ID SCZ | |
DB_ID:1553 | Class I PI3K signaling events | 1288 | 32 | 9.86 | 3.25 | 6.83e-09 | 6.50e-08 | ID SCZ | |
DB_ID:1531 | PAR1-mediated thrombin signaling events | 1299 | 32 | 9.94 | 3.22 | 8.34e-09 | 6.50e-08 | ID SCZ | |
DB_ID:1519 | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling | 1288 | 32 | 9.86 | 3.25 | 6.83e-09 | 6.50e-08 | ID SCZ | |
DB_ID:1529 | IFN-gamma pathway | 1296 | 32 | 9.92 | 3.23 | 7.90e-09 | 6.50e-08 | ID SCZ | |
DB_ID:1594 | S1P1 pathway | 1288 | 32 | 9.86 | 3.25 | 6.83e-09 | 6.50e-08 | ID SCZ | |
DB_ID:1615 | Arf6 trafficking events | 1288 | 32 | 9.86 | 3.25 | 6.83e-09 | 6.50e-08 | ID SCZ | |
DB_ID:1564 | IL3-mediated signaling events | 1295 | 32 | 9.91 | 3.23 | 7.76e-09 | 6.50e-08 | ID SCZ | |
DB_ID:1602 | ErbB1 downstream signaling | 1288 | 32 | 9.86 | 3.25 | 6.83e-09 | 6.50e-08 | ID SCZ | |
DB_ID:1482 | IGF1 pathway | 1291 | 32 | 9.88 | 3.24 | 7.22e-09 | 6.50e-08 | ID SCZ | |
DB_ID:1492 | Glypican 1 network | 1299 | 32 | 9.94 | 3.22 | 8.34e-09 | 6.50e-08 | ID SCZ | |
DB_ID:1648 | Class I PI3K signaling events mediated by Akt | 1288 | 32 | 9.86 | 3.25 | 6.83e-09 | 6.50e-08 | ID SCZ | |
DB_ID:1491 | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) | 1293 | 32 | 9.89 | 3.23 | 7.48e-09 | 6.50e-08 | ID SCZ | |
DB_ID:1461 | GMCSF-mediated signaling events | 1292 | 32 | 9.89 | 3.24 | 7.35e-09 | 6.50e-08 | ID SCZ | |
DB_ID:1603 | EGFR-dependent Endothelin signaling events | 1289 | 32 | 9.86 | 3.24 | 6.96e-09 | 6.50e-08 | ID SCZ | |
DB_ID:1550 | EGF receptor (ErbB1) signaling pathway | 1288 | 32 | 9.86 | 3.25 | 6.83e-09 | 6.50e-08 | ID SCZ | |
DB_ID:1552 | Thrombin/protease-activated receptor (PAR) pathway | 1300 | 32 | 9.95 | 3.22 | 8.50e-09 | 6.50e-08 | ID SCZ | |
DB_ID:1627 | IL5-mediated signaling events | 1292 | 32 | 9.89 | 3.24 | 7.35e-09 | 6.50e-08 | ID SCZ | |
DB_ID:1459 | Glypican pathway | 1338 | 33 | 10.24 | 3.22 | 4.67e-09 | 6.50e-08 | ID SCZ | |
DB_ID:1466 | Insulin Pathway | 1288 | 32 | 9.86 | 3.25 | 6.83e-09 | 6.50e-08 | ID SCZ | |
DB_ID:1540 | PDGFR-beta signaling pathway | 1288 | 32 | 9.86 | 3.25 | 6.83e-09 | 6.50e-08 | ID SCZ | |
DB_ID:1585 | Arf6 downstream pathway | 1288 | 32 | 9.86 | 3.25 | 6.83e-09 | 6.50e-08 | ID SCZ | |
DB_ID:1571 | mTOR signaling pathway | 1288 | 32 | 9.86 | 3.25 | 6.83e-09 | 6.50e-08 | ID SCZ | |
DB_ID:1554 | Arf6 signaling events | 1288 | 32 | 9.86 | 3.25 | 6.83e-09 | 6.50e-08 | ID SCZ | |
DB_ID:1497 | PDGF receptor signaling network | 1293 | 32 | 9.89 | 3.23 | 7.48e-09 | 6.50e-08 | ID SCZ | |
DB_ID:1574 | Signaling events mediated by focal adhesion kinase | 1288 | 32 | 9.86 | 3.25 | 6.83e-09 | 6.50e-08 | ID SCZ | |
DB_ID:1649 | LKB1 signaling events | 1308 | 32 | 10.01 | 3.20 | 9.81e-09 | 7.32e-08 | ID SCZ | |
DB_ID:1665 | NOTCH | 57 | 8 | 0.44 | 18.34 | 1.29e-08 | 9.40e-08 | SCZ | |
DB_ID:1488 | CDC42 signaling events | 757 | 23 | 5.79 | 3.97 | 2.87e-08 | 2.04e-07 | ID SCZ | |
DB_ID:1456 | Regulation of CDC42 activity | 770 | 23 | 5.89 | 3.90 | 3.91e-08 | 2.72e-07 | ID SCZ | |
DB_ID:20 | Axon guidance | 219 | 12 | 1.68 | 7.16 | 1.50e-07 | 1.02e-06 | ID SCZ | |
DB_ID:150 | Transmission across Chemical Synapses | 121 | 9 | 0.93 | 9.72 | 4.30e-07 | 2.86e-06 | EE ID SCZ | |
DB_ID:1604 | Syndecan-4-mediated signaling events | 209 | 11 | 1.60 | 6.88 | 7.41e-07 | 4.82e-06 | ID SCZ | |
DB_ID:1546 | Integrin-linked kinase signaling | 656 | 19 | 5.02 | 3.79 | 9.59e-07 | 6.11e-06 | ID SCZ | |
DB_ID:1565 | AP-1 transcription factor network | 623 | 18 | 4.77 | 3.78 | 1.92e-06 | 1.20e-05 | ID SCZ | |
DB_ID:164 | GABA synthesis, release, reuptake and degradation | 17 | 4 | 0.13 | 30.75 | 7.41e-06 | 4.53e-05 | ID | |
DB_ID:11 | Developmental Biology | 433 | 14 | 3.31 | 4.23 | 7.67e-06 | 4.60e-05 | ID SCZ | |
DB_ID:965 | Na+/Cl- dependent neurotransmitter transporters | 18 | 4 | 0.14 | 29.04 | 9.46e-06 | 5.57e-05 | - | |
DB_ID:1535 | Noncanonical Wnt signaling pathway | 182 | 9 | 1.39 | 6.46 | 1.25e-05 | 7.22e-05 | ID SCZ | |
DB_ID:254 | Signalling by NGF | 143 | 8 | 1.09 | 7.31 | 1.57e-05 | 8.90e-05 | SCZ | |
DB_ID:863 | Deadenylation of mRNA | 22 | 4 | 0.17 | 23.76 | 2.21e-05 | 0.0001 | - | |
DB_ID:1435 | Wnt signaling network | 200 | 9 | 1.53 | 5.88 | 2.64e-05 | 0.0001 | ID SCZ | |
DB_ID:18 | Sema4D induced cell migration and growth-cone collapse | 22 | 4 | 0.17 | 23.76 | 2.21e-05 | 0.0001 | SCZ | |
DB_ID:289 | NGF signalling via TRKA from the plasma membrane | 107 | 7 | 0.82 | 8.55 | 1.95e-05 | 0.0001 | SCZ | |
DB_ID:937 | Transmembrane transport of small molecules | 379 | 12 | 2.90 | 4.14 | 4.18e-05 | 0.0002 | EE | |
DB_ID:331 | Signal Transduction | 1231 | 24 | 9.42 | 2.55 | 3.27e-05 | 0.0002 | - | |
DB_ID:466 | Signaling by PDGF | 78 | 6 | 0.60 | 10.05 | 3.10e-05 | 0.0002 | SCZ | |
DB_ID:16 | Sema4D in semaphorin signaling | 27 | 4 | 0.21 | 19.36 | 5.14e-05 | 0.0002 | SCZ | |
DB_ID:1530 | Regulation of RAC1 activity | 205 | 9 | 1.57 | 5.74 | 3.20e-05 | 0.0002 | ID | |
DB_ID:1471 | Glypican 3 network | 206 | 9 | 1.58 | 5.71 | 3.33e-05 | 0.0002 | ID SCZ | |
DB_ID:1572 | RAC1 signaling pathway | 205 | 9 | 1.57 | 5.74 | 3.20e-05 | 0.0002 | ID | |
DB_ID:1650 | Regulation of RhoA activity | 205 | 9 | 1.57 | 5.74 | 3.20e-05 | 0.0002 | ID | |
DB_ID:157 | Neurotransmitter Release Cycle | 26 | 4 | 0.20 | 20.11 | 4.41e-05 | 0.0002 | ID | |
DB_ID:1647 | RhoA signaling pathway | 205 | 9 | 1.57 | 5.74 | 3.20e-05 | 0.0002 | ID | |
DB_ID:646 | Amine compound SLC transporters | 29 | 4 | 0.22 | 18.03 | 6.87e-05 | 0.0003 | - | |
DB_ID:21 | Semaphorin interactions | 64 | 5 | 0.49 | 10.21 | 0.0001 | 0.0004 | SCZ | |
DB_ID:1600 | TNF receptor signaling pathway | 299 | 10 | 2.29 | 4.37 | 0.0001 | 0.0004 | ID | |
DB_ID:1625 | Notch signaling pathway | 94 | 6 | 0.72 | 8.34 | 8.87e-05 | 0.0004 | ID SCZ | |
DB_ID:1457 | Notch-mediated HES/HEY network | 94 | 6 | 0.72 | 8.34 | 8.87e-05 | 0.0004 | ID SCZ | |
DB_ID:851 | Regulation of Insulin Secretion by Acetylcholine | 3 | 2 | 0.02 | 87.13 | 0.0002 | 0.0008 | - | |
DB_ID:1467 | C-MYC pathway | 149 | 7 | 1.14 | 6.14 | 0.0002 | 0.0008 | SCZ | |
DB_ID:1542 | Canonical Wnt signaling pathway | 155 | 7 | 1.19 | 5.90 | 0.0002 | 0.0008 | ID SCZ | |
DB_ID:634 | Metabolism | 824 | 17 | 6.31 | 2.70 | 0.0002 | 0.0008 | SCZ | |
DB_ID:467 | Downstream signal transduction | 75 | 5 | 0.57 | 8.71 | 0.0003 | 0.0011 | SCZ | |
DB_ID:1490 | Syndecan-3-mediated signaling events | 17 | 3 | 0.13 | 23.06 | 0.0003 | 0.0011 | - | |
DB_ID:161 | Reuptake of GABA | 4 | 2 | 0.03 | 65.34 | 0.0003 | 0.0011 | - | |
DB_ID:862 | Deadenylation-dependent mRNA decay | 46 | 4 | 0.35 | 11.36 | 0.0004 | 0.0015 | - | |
DB_ID:1644 | BMP receptor signaling | 226 | 8 | 1.73 | 4.63 | 0.0004 | 0.0015 | - | |
DB_ID:1621 | Presenilin action in Notch and Wnt signaling | 46 | 4 | 0.35 | 11.36 | 0.0004 | 0.0015 | - | |
DB_ID:812 | Integration of energy metabolism | 83 | 5 | 0.64 | 7.87 | 0.0005 | 0.0018 | SCZ | |
DB_ID:450 | Signaling by Notch | 21 | 3 | 0.16 | 18.67 | 0.0005 | 0.0018 | - | |
DB_ID:482 | G alpha (12/13) signalling events | 21 | 3 | 0.16 | 18.67 | 0.0005 | 0.0018 | - | |
DB_ID:809 | Regulation of Insulin Secretion | 48 | 4 | 0.37 | 10.89 | 0.0005 | 0.0018 | - | |
DB_ID:1547 | Regulation of nuclear beta catenin signaling and target gene transcription | 135 | 6 | 1.03 | 5.81 | 0.0006 | 0.0021 | ID SCZ | |
DB_ID:1549 | p38 MAPK signaling pathway | 189 | 7 | 1.45 | 4.84 | 0.0007 | 0.0024 | - | |
DB_ID:64 | Hemostasis | 376 | 10 | 2.88 | 3.48 | 0.0007 | 0.0024 | - | |
DB_ID:973 | Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds | 95 | 5 | 0.73 | 6.88 | 0.0008 | 0.0027 | ID | |
DB_ID:562 | Vitamin D (calciferol) metabolism | 7 | 2 | 0.05 | 37.34 | 0.0012 | 0.0039 | - | |
DB_ID:1498 | EphrinB-EPHB pathway | 60 | 4 | 0.46 | 8.71 | 0.0012 | 0.0039 | - | |
DB_ID:1469 | Stabilization and expansion of the E-cadherin adherens junction | 275 | 8 | 2.10 | 3.80 | 0.0014 | 0.0045 | ID SCZ | |
DB_ID:956 | Nephrin interactions | 29 | 3 | 0.22 | 13.52 | 0.0014 | 0.0045 | - | |
DB_ID:1544 | E-cadherin signaling in the nascent adherens junction | 275 | 8 | 2.10 | 3.80 | 0.0014 | 0.0045 | ID SCZ | |
DB_ID:1617 | E-cadherin signaling events | 280 | 8 | 2.14 | 3.73 | 0.0015 | 0.0047 | ID SCZ | |
DB_ID:241 | PI3K/AKT activation | 30 | 3 | 0.23 | 13.07 | 0.0015 | 0.0047 | EE | |
DB_ID:463 | A third proteolytic cleavage releases NICD | 8 | 2 | 0.06 | 32.67 | 0.0016 | 0.0048 | - | |
DB_ID:910 | Import of palmitoyl-CoA into the mitochondrial matrix | 8 | 2 | 0.06 | 32.67 | 0.0016 | 0.0048 | - | |
DB_ID:446 | Notch receptor binds with a ligand | 8 | 2 | 0.06 | 32.67 | 0.0016 | 0.0048 | - | |
DB_ID:472 | Signaling by SCF-KIT | 66 | 4 | 0.51 | 7.92 | 0.0017 | 0.0050 | - | |
DB_ID:325 | Downstream signaling of activated FGFR | 66 | 4 | 0.51 | 7.92 | 0.0017 | 0.0050 | SCZ | |
DB_ID:1536 | Regulation of p38-alpha and p38-beta | 164 | 6 | 1.25 | 4.78 | 0.0017 | 0.0050 | - | |
DB_ID:1641 | Effects of Botulinum toxin | 9 | 2 | 0.07 | 29.04 | 0.0020 | 0.0057 | - | |
DB_ID:159 | Serotonin Neurotransmitter Release Cycle | 9 | 2 | 0.07 | 29.04 | 0.0020 | 0.0057 | - | |
DB_ID:462 | Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor | 9 | 2 | 0.07 | 29.04 | 0.0020 | 0.0057 | - | |
DB_ID:155 | Dopamine Neurotransmitter Release Cycle | 9 | 2 | 0.07 | 29.04 | 0.0020 | 0.0057 | - | |
DB_ID:1500 | IL1-mediated signaling events | 234 | 7 | 1.79 | 3.91 | 0.0023 | 0.0064 | - | |
DB_ID:530 | Integrin cell surface interactions | 72 | 4 | 0.55 | 7.26 | 0.0023 | 0.0064 | - | |
DB_ID:178 | Potassium Channels | 76 | 4 | 0.58 | 6.88 | 0.0028 | 0.0077 | EE ID | |
DB_ID:154 | Acetylcholine Neurotransmitter Release Cycle | 11 | 2 | 0.08 | 23.76 | 0.0031 | 0.0083 | - | |
DB_ID:158 | Glutamate Neurotransmitter Release Cycle | 11 | 2 | 0.08 | 23.76 | 0.0031 | 0.0083 | - | |
DB_ID:156 | Norepinephrine Neurotransmitter Release Cycle | 11 | 2 | 0.08 | 23.76 | 0.0031 | 0.0083 | - | |
DB_ID:943 | SLC-mediated transmembrane transport | 248 | 7 | 1.90 | 3.69 | 0.0032 | 0.0084 | ID | |
DB_ID:44 | L1CAM interactions | 79 | 4 | 0.60 | 6.62 | 0.0032 | 0.0084 | ID | |
DB_ID:171 | Voltage gated Potassium channels | 39 | 3 | 0.30 | 10.05 | 0.0033 | 0.0086 | EE ID | |
DB_ID:1494 | N-cadherin signaling events | 251 | 7 | 1.92 | 3.64 | 0.0034 | 0.0088 | ID SCZ | |
DB_ID:1545 | EPHB forward signaling | 40 | 3 | 0.31 | 9.80 | 0.0036 | 0.0093 | - | |
DB_ID:246 | ERK/MAPK targets | 12 | 2 | 0.09 | 21.78 | 0.0037 | 0.0094 | - | |
DB_ID:919 | Fatty acid, triacylglycerol, and ketone body metabolism | 83 | 4 | 0.64 | 6.30 | 0.0038 | 0.0096 | - | |
DB_ID:984 | Metabolism of lipids and lipoproteins | 258 | 7 | 1.97 | 3.55 | 0.0039 | 0.0098 | - | |
DB_ID:56 | Platelet activation, signaling and aggregation | 139 | 5 | 1.06 | 4.70 | 0.0044 | 0.0109 | - | |
DB_ID:130 | Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | 89 | 4 | 0.68 | 5.87 | 0.0049 | 0.0121 | EE ID SCZ | |
DB_ID:245 | Nuclear Events (kinase and transcription factor activation) | 15 | 2 | 0.11 | 17.43 | 0.0057 | 0.0138 | - | |
DB_ID:1475 | Validated nuclear estrogen receptor beta network | 15 | 2 | 0.11 | 17.43 | 0.0057 | 0.0138 | - | |
DB_ID:1660 | Alpha6Beta4Integrin | 48 | 3 | 0.37 | 8.17 | 0.0060 | 0.0145 | - | |
DB_ID:306 | Signaling by FGFR | 95 | 4 | 0.73 | 5.50 | 0.0062 | 0.0148 | SCZ | |
DB_ID:1659 | Hedgehog | 16 | 2 | 0.12 | 16.34 | 0.0065 | 0.0152 | - | |
DB_ID:479 | Glucagon-type ligand receptors | 16 | 2 | 0.12 | 16.34 | 0.0065 | 0.0152 | - | |
DB_ID:1438 | LPA4-mediated signaling events | 16 | 2 | 0.12 | 16.34 | 0.0065 | 0.0152 | SCZ | |
DB_ID:1524 | Signaling mediated by p38-alpha and p38-beta | 50 | 3 | 0.38 | 7.84 | 0.0067 | 0.0154 | - | |
DB_ID:516 | TCR signaling | 50 | 3 | 0.38 | 7.84 | 0.0067 | 0.0154 | - | |
DB_ID:330 | Signaling by EGFR | 98 | 4 | 0.75 | 5.33 | 0.0069 | 0.0158 | SCZ | |
DB_ID:847 | PKA activation in glucagon signalling | 17 | 2 | 0.13 | 15.38 | 0.0074 | 0.0166 | SCZ | |
DB_ID:1501 | Caspase cascade in apoptosis | 52 | 3 | 0.40 | 7.54 | 0.0074 | 0.0166 | ID | |
DB_ID:759 | Activated AMPK stimulates fatty-acid oxidation in muscle | 18 | 2 | 0.14 | 14.52 | 0.0082 | 0.0183 | - | |
DB_ID:1006 | Costimulation by the CD28 family | 55 | 3 | 0.42 | 7.13 | 0.0087 | 0.0193 | - | |
DB_ID:1512 | Posttranslational regulation of adherens junction stability and dissassembly | 231 | 6 | 1.77 | 3.39 | 0.0090 | 0.0198 | ID SCZ | |
DB_ID:872 | Citric acid cycle (TCA cycle) | 19 | 2 | 0.15 | 13.76 | 0.0092 | 0.0201 | - | |
DB_ID:1611 | Regulation of nuclear SMAD2/3 signaling | 305 | 7 | 2.33 | 3.00 | 0.0095 | 0.0203 | SCZ | |
DB_ID:1510 | TGF-beta receptor signaling | 305 | 7 | 2.33 | 3.00 | 0.0095 | 0.0203 | SCZ | |
DB_ID:1440 | Regulation of cytoplasmic and nuclear SMAD2/3 signaling | 305 | 7 | 2.33 | 3.00 | 0.0095 | 0.0203 | SCZ | |
DB_ID:22 | NCAM signaling for neurite out-growth | 57 | 3 | 0.44 | 6.88 | 0.0096 | 0.0204 | - | |
DB_ID:864 | Metabolism of mRNA | 235 | 6 | 1.80 | 3.34 | 0.0098 | 0.0207 | - | |
DB_ID:1107 | MAPK targets/ Nuclear events mediated by MAP kinases | 21 | 2 | 0.16 | 12.45 | 0.0111 | 0.0230 | - | |
DB_ID:1458 | p38 signaling mediated by MAPKAP kinases | 21 | 2 | 0.16 | 12.45 | 0.0111 | 0.0230 | - | |
DB_ID:302 | PIP3 activates AKT signaling | 21 | 2 | 0.16 | 12.45 | 0.0111 | 0.0230 | EE | |
DB_ID:515 | Adaptive Immune System | 243 | 6 | 1.86 | 3.23 | 0.0114 | 0.0234 | - | |
DB_ID:458 | Signaling by GPCR | 823 | 13 | 6.30 | 2.06 | 0.0116 | 0.0237 | - | |
DB_ID:1612 | ALK1 signaling events | 321 | 7 | 2.46 | 2.85 | 0.0123 | 0.0246 | SCZ | |
DB_ID:484 | G alpha (z) signalling events | 22 | 2 | 0.17 | 11.88 | 0.0122 | 0.0246 | SCZ | |
DB_ID:1551 | p75(NTR)-mediated signaling | 178 | 5 | 1.36 | 3.67 | 0.0122 | 0.0246 | - | |
DB_ID:1444 | Validated targets of C-MYC transcriptional repression | 63 | 3 | 0.48 | 6.22 | 0.0126 | 0.0250 | - | |
DB_ID:935 | Cell-Cell communication | 117 | 4 | 0.90 | 4.47 | 0.0127 | 0.0251 | - | |
DB_ID:1583 | ALK1 pathway | 324 | 7 | 2.48 | 2.82 | 0.0129 | 0.0253 | SCZ | |
DB_ID:116 | NCAM1 interactions | 23 | 2 | 0.18 | 11.36 | 0.0133 | 0.0259 | SCZ | |
DB_ID:981 | Regulation of Water Balance by Renal Aquaporins | 24 | 2 | 0.18 | 10.89 | 0.0144 | 0.0274 | SCZ | |
DB_ID:28 | CDO in myogenesis | 24 | 2 | 0.18 | 10.89 | 0.0144 | 0.0274 | - | |
DB_ID:1623 | Regulation of retinoblastoma protein | 66 | 3 | 0.51 | 5.94 | 0.0142 | 0.0274 | ID | |
DB_ID:29 | Myogenesis | 24 | 2 | 0.18 | 10.89 | 0.0144 | 0.0274 | - | |
DB_ID:338 | Calmodulin induced events | 25 | 2 | 0.19 | 10.46 | 0.0156 | 0.0291 | SCZ | |
DB_ID:1070 | Steroid hormones | 25 | 2 | 0.19 | 10.46 | 0.0156 | 0.0291 | - | |
DB_ID:339 | CaM pathway | 25 | 2 | 0.19 | 10.46 | 0.0156 | 0.0291 | SCZ | |
DB_ID:459 | GPCR ligand binding | 338 | 7 | 2.59 | 2.71 | 0.0159 | 0.0295 | - | |
DB_ID:323 | Phospholipase C-mediated cascade | 27 | 2 | 0.21 | 9.68 | 0.0181 | 0.0322 | SCZ | |
DB_ID:493 | Ca-dependent events | 27 | 2 | 0.21 | 9.68 | 0.0181 | 0.0322 | SCZ | |
DB_ID:336 | DAG and IP3 signaling | 27 | 2 | 0.21 | 9.68 | 0.0181 | 0.0322 | SCZ | |
DB_ID:68 | Cell surface interactions at the vascular wall | 72 | 3 | 0.55 | 5.45 | 0.0180 | 0.0322 | - | |
DB_ID:321 | PI-3K cascade | 27 | 2 | 0.21 | 9.68 | 0.0181 | 0.0322 | EE | |
DB_ID:992 | Aquaporin-mediated transport | 27 | 2 | 0.21 | 9.68 | 0.0181 | 0.0322 | SCZ | |
DB_ID:1559 | FAS (CD95) signaling pathway | 130 | 4 | 0.99 | 4.02 | 0.0180 | 0.0322 | ID | |
DB_ID:166 | CREB phosphorylation through the activation of Ras | 28 | 2 | 0.21 | 9.33 | 0.0194 | 0.0343 | ID | |
DB_ID:1523 | Reelin signaling pathway | 29 | 2 | 0.22 | 9.01 | 0.0207 | 0.0362 | ID SCZ | |
DB_ID:337 | EGFR interacts with phospholipase C-gamma | 29 | 2 | 0.22 | 9.01 | 0.0207 | 0.0362 | SCZ | |
DB_ID:1581 | Syndecan-2-mediated signaling events | 77 | 3 | 0.59 | 5.09 | 0.0214 | 0.0372 | - | |
DB_ID:240 | PLC-gamma1 signalling | 30 | 2 | 0.23 | 8.71 | 0.0221 | 0.0374 | SCZ | |
DB_ID:1108 | MAP kinase activation in TLR cascade | 30 | 2 | 0.23 | 8.71 | 0.0221 | 0.0374 | - | |
DB_ID:865 | Metabolism of RNA | 282 | 6 | 2.16 | 2.78 | 0.0221 | 0.0374 | - | |
DB_ID:1548 | Ephrin B reverse signaling | 30 | 2 | 0.23 | 8.71 | 0.0221 | 0.0374 | - | |
DB_ID:1664 | EGFR1 | 138 | 4 | 1.06 | 3.79 | 0.0219 | 0.0374 | SCZ | |
DB_ID:522 | Immune System | 532 | 9 | 4.07 | 2.21 | 0.0223 | 0.0375 | ID SCZ | |
DB_ID:1484 | Lissencephaly gene (LIS1) in neuronal migration and development | 31 | 2 | 0.24 | 8.43 | 0.0235 | 0.0389 | - | |
DB_ID:476 | G alpha (s) signalling events | 31 | 2 | 0.24 | 8.43 | 0.0235 | 0.0389 | SCZ | |
DB_ID:546 | Pyruvate metabolism and Citric Acid (TCA) cycle | 31 | 2 | 0.24 | 8.43 | 0.0235 | 0.0389 | - | |
DB_ID:1493 | Validated targets of C-MYC transcriptional activation | 81 | 3 | 0.62 | 4.84 | 0.0244 | 0.0399 | ID SCZ | |
DB_ID:308 | GAB1 signalosome | 32 | 2 | 0.24 | 8.17 | 0.0249 | 0.0399 | EE | |
DB_ID:43 | Recycling pathway of L1 | 32 | 2 | 0.24 | 8.17 | 0.0249 | 0.0399 | - | |
DB_ID:576 | Metabolism of steroid hormones and vitamins A and D | 32 | 2 | 0.24 | 8.17 | 0.0249 | 0.0399 | - | |
DB_ID:580 | Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | 32 | 2 | 0.24 | 8.17 | 0.0249 | 0.0399 | - | |
DB_ID:475 | G alpha (i) signalling events | 32 | 2 | 0.24 | 8.17 | 0.0249 | 0.0399 | SCZ | |
DB_ID:846 | Glucagon signaling in metabolic regulation | 33 | 2 | 0.25 | 7.92 | 0.0264 | 0.0421 | SCZ | |
DB_ID:1024 | RNA Polymerase III Abortive And Retractive Initiation | 34 | 2 | 0.26 | 7.69 | 0.0279 | 0.0431 | - | |
DB_ID:1560 | C-MYB transcription factor network | 85 | 3 | 0.65 | 4.61 | 0.0277 | 0.0431 | - | |
DB_ID:1023 | RNA Polymerase III Transcription | 34 | 2 | 0.26 | 7.69 | 0.0279 | 0.0431 | - | |
DB_ID:140 | Activation of NMDA receptor upon glutamate binding and postsynaptic events | 34 | 2 | 0.26 | 7.69 | 0.0279 | 0.0431 | ID SCZ | |
DB_ID:1569 | Glucocorticoid receptor signaling | 85 | 3 | 0.65 | 4.61 | 0.0277 | 0.0431 | SCZ | |
DB_ID:142 | Post NMDA receptor activation events | 34 | 2 | 0.26 | 7.69 | 0.0279 | 0.0431 | ID SCZ | |
DB_ID:27 | Signal transduction by L1 | 35 | 2 | 0.27 | 7.47 | 0.0294 | 0.0450 | - | |
DB_ID:1005 | Downstream TCR signaling | 35 | 2 | 0.27 | 7.47 | 0.0294 | 0.0450 | - | |
DB_ID:495 | Amine ligand-binding receptors | 36 | 2 | 0.28 | 7.26 | 0.0310 | 0.0467 | - | |
DB_ID:1000 | CD28 co-stimulation | 36 | 2 | 0.28 | 7.26 | 0.0310 | 0.0467 | - | |
DB_ID:192 | GABA receptor activation | 36 | 2 | 0.28 | 7.26 | 0.0310 | 0.0467 | EE SCZ |