Neuropsychiatric De novo Mutations Database

Wikipathways

Other pathways: Gene Ontology Transcription Factor Target MicroRNA Target KEGG Wikipathways Pathway Commons

Including 38 wikipathways in ASD, 22 in ID, 20 in EE and 39 in SCZ.

wiki accession	wiki pathway name	Number of reference genes	Number of genes	Expected number	Ratio of entrichment	Raw P_Value	Adjusted P_Value	Other disease
DB_ID:1637	Proteoglycan syndecan-mediated signaling events	1345	37	10.29	3.60	2.43e-11	7.44e-09	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| PSEN1 \| TF \| CSDE1 \| CAD \| CHD7 \| SUV420H1 \| EPHB2 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| CASK \| APH1A \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| SVIL \| PDGFD \| TLE1 \| MAPK13 \| APAF1 \| ROCK1 \| RPS6KA3 \| RGMA
DB_ID:1499	Integrin family cell surface interactions	1378	36	10.54	3.41	1.89e-10	2.89e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| LAMB3 \| CSDE1 \| CAD \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| C3 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| PAOX \| HSPA4 \| FBN1 \| SVIL \| PDGFD \| TLE1 \| MAPK13 \| APAF1 \| ROCK1 \| RPS6KA3 \| RGMA
DB_ID:1517	Beta1 integrin cell surface interactions	1351	35	10.34	3.39	4.30e-10	4.39e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| LAMB3 \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| PAOX \| HSPA4 \| FBN1 \| SVIL \| TLE1 \| PDGFD \| MAPK13 \| APAF1 \| ROCK1 \| RPS6KA3 \| RGMA
DB_ID:1619	Endothelins	1307	34	10.00	3.40	6.99e-10	5.35e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CSDE1 \| CAD \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| GNAS \| TCF7L1 \| HSPA4 \| ADCY5 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| APAF1 \| ROCK1 \| RPS6KA3 \| RGMA
DB_ID:1472	Nectin adhesion pathway	1295	33	9.91	3.33	2.11e-09	6.34e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| PTPRM \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| RGMA
DB_ID:1556	Plasma membrane estrogen receptor signaling	1301	33	9.96	3.31	2.36e-09	6.34e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CSDE1 \| CAD \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| GNAS \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| RGMA
DB_ID:1516	Signaling events mediated by VEGFR1 and VEGFR2	1296	33	9.92	3.33	2.15e-09	6.34e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| MYOF \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| RGMA
DB_ID:1635	Sphingosine 1-phosphate (S1P) pathway	1311	33	10.03	3.29	2.84e-09	6.34e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| MADD \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| RGMA
DB_ID:143	Neuronal System	188	13	1.44	9.04	2.83e-09	6.34e-08	EE ID SCZ
GABRB3 \| RIMS1 \| ADCY5 \| KCNMA1 \| SLC6A3 \| KCND2 \| KCNC1 \| SLC6A1 \| STXBP1 \| SLC6A13 \| RPS6KA3 \| KCNS1
DB_ID:1575	VEGF and VEGFR signaling network	1304	33	9.98	3.31	2.50e-09	6.34e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| MYOF \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| RGMA
DB_ID:1480	TRAIL signaling pathway	1328	34	10.16	3.35	1.05e-09	6.34e-08	ID SCZ
DNMT3A \| TSC2 \| SLK \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CSDE1 \| CAD \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| MADD \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| APAF1 \| ROCK1 \| RPS6KA3 \| RGMA
DB_ID:1454	Syndecan-1-mediated signaling events	1300	33	9.95	3.32	2.31e-09	6.34e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| CASK \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| RGMA
DB_ID:1573	ErbB receptor signaling network	1312	33	10.04	3.29	2.90e-09	6.34e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| GRIN2B \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| RGMA
DB_ID:1578	Alpha9 beta1 integrin signaling events	1305	33	9.99	3.30	2.54e-09	6.34e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| PAOX \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| RGMA
DB_ID:1509	Internalization of ErbB1	1288	32	9.86	3.25	6.83e-09	6.50e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| MEF2C
DB_ID:1553	Class I PI3K signaling events	1288	32	9.86	3.25	6.83e-09	6.50e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| MEF2C
DB_ID:1531	PAR1-mediated thrombin signaling events	1299	32	9.94	3.22	8.34e-09	6.50e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| MEF2C
DB_ID:1519	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling	1288	32	9.86	3.25	6.83e-09	6.50e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| MEF2C
DB_ID:1529	IFN-gamma pathway	1296	32	9.92	3.23	7.90e-09	6.50e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| MEF2C
DB_ID:1594	S1P1 pathway	1288	32	9.86	3.25	6.83e-09	6.50e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| MEF2C
DB_ID:1615	Arf6 trafficking events	1288	32	9.86	3.25	6.83e-09	6.50e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| MEF2C
DB_ID:1564	IL3-mediated signaling events	1295	32	9.91	3.23	7.76e-09	6.50e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| MEF2C
DB_ID:1602	ErbB1 downstream signaling	1288	32	9.86	3.25	6.83e-09	6.50e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| MEF2C
DB_ID:1482	IGF1 pathway	1291	32	9.88	3.24	7.22e-09	6.50e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| MEF2C
DB_ID:1492	Glypican 1 network	1299	32	9.94	3.22	8.34e-09	6.50e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| MEF2C
DB_ID:1648	Class I PI3K signaling events mediated by Akt	1288	32	9.86	3.25	6.83e-09	6.50e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| MEF2C
DB_ID:1491	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)	1293	32	9.89	3.23	7.48e-09	6.50e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| MEF2C
DB_ID:1461	GMCSF-mediated signaling events	1292	32	9.89	3.24	7.35e-09	6.50e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| MEF2C
DB_ID:1603	EGFR-dependent Endothelin signaling events	1289	32	9.86	3.24	6.96e-09	6.50e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| MEF2C
DB_ID:1550	EGF receptor (ErbB1) signaling pathway	1288	32	9.86	3.25	6.83e-09	6.50e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| MEF2C
DB_ID:1552	Thrombin/protease-activated receptor (PAR) pathway	1300	32	9.95	3.22	8.50e-09	6.50e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| MEF2C
DB_ID:1627	IL5-mediated signaling events	1292	32	9.89	3.24	7.35e-09	6.50e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| MEF2C
DB_ID:1459	Glypican pathway	1338	33	10.24	3.22	4.67e-09	6.50e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CSDE1 \| CHD7 \| CAD \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| RGMA
DB_ID:1466	Insulin Pathway	1288	32	9.86	3.25	6.83e-09	6.50e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| MEF2C
DB_ID:1540	PDGFR-beta signaling pathway	1288	32	9.86	3.25	6.83e-09	6.50e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| MEF2C
DB_ID:1585	Arf6 downstream pathway	1288	32	9.86	3.25	6.83e-09	6.50e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| MEF2C
DB_ID:1571	mTOR signaling pathway	1288	32	9.86	3.25	6.83e-09	6.50e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| MEF2C
DB_ID:1554	Arf6 signaling events	1288	32	9.86	3.25	6.83e-09	6.50e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| MEF2C
DB_ID:1497	PDGF receptor signaling network	1293	32	9.89	3.23	7.48e-09	6.50e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| MEF2C
DB_ID:1574	Signaling events mediated by focal adhesion kinase	1288	32	9.86	3.25	6.83e-09	6.50e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| MEF2C
DB_ID:1649	LKB1 signaling events	1308	32	10.01	3.20	9.81e-09	7.32e-08	ID SCZ
DNMT3A \| TSC2 \| TCF3 \| PPM1D \| DGKA \| NCKAP1 \| PRKCA \| TF \| CAD \| CSDE1 \| SUV420H1 \| PTEN \| CHD8 \| ITGB3 \| PAK2 \| TBL1XR1 \| LRP1 \| CUL3 \| ITGA5 \| EIF4A1 \| SMARCC2 \| TCF7L1 \| HSPA4 \| TLE1 \| PDGFD \| SVIL \| MAPK13 \| ROCK1 \| APAF1 \| RPS6KA3 \| MEF2C
DB_ID:1665	NOTCH	57	8	0.44	18.34	1.29e-08	9.40e-08	SCZ
HIVEP3 \| DLL1 \| APH1A \| TCF3 \| PIK3R2 \| TLE1 \| NOTCH3
DB_ID:1488	CDC42 signaling events	757	23	5.79	3.97	2.87e-08	2.04e-07	ID SCZ
ABI2 \| TSC2 \| TBL1XR1 \| TCF3 \| TRIO \| CUL3 \| DGKA \| SPATA13 \| NCKAP1 \| SMARCC2 \| PRKCA \| TF \| TCF7L1 \| SUV420H1 \| PTEN \| CHD8 \| PAK2 \| SVIL \| TLE1 \| MAPK13 \| ROCK1 \| RPS6KA3
DB_ID:1456	Regulation of CDC42 activity	770	23	5.89	3.90	3.91e-08	2.72e-07	ID SCZ
ABI2 \| TSC2 \| TBL1XR1 \| TCF3 \| TRIO \| CUL3 \| DGKA \| SPATA13 \| NCKAP1 \| SMARCC2 \| PRKCA \| TF \| TCF7L1 \| SUV420H1 \| PTEN \| CHD8 \| PAK2 \| SVIL \| TLE1 \| MAPK13 \| ROCK1 \| RPS6KA3
DB_ID:20	Axon guidance	219	12	1.68	7.16	1.50e-07	1.02e-06	ID SCZ
EPHB2 \| ANK2 \| PAK2 \| ITGB3 \| MYH9 \| CACNA1S \| ROCK1 \| CACNA1D \| MYH10 \| PLXNB1 \| RPS6KA3
DB_ID:150	Transmission across Chemical Synapses	121	9	0.93	9.72	4.30e-07	2.86e-06	EE ID SCZ
GABRB3 \| RIMS1 \| ADCY5 \| SLC6A3 \| SLC6A1 \| STXBP1 \| SLC6A13 \| RPS6KA3
DB_ID:1604	Syndecan-4-mediated signaling events	209	11	1.60	6.88	7.41e-07	4.82e-06	ID SCZ
CHD7 \| TCF7L1 \| TBL1XR1 \| CHD8 \| CUL3 \| SVIL \| ITGA5 \| TLE1 \| ROCK1 \| PRKCA
DB_ID:1546	Integrin-linked kinase signaling	656	19	5.02	3.79	9.59e-07	6.11e-06	ID SCZ
TSC2 \| TBL1XR1 \| TCF3 \| NACA \| CUL3 \| DGKA \| SMARCC2 \| PRKCA \| TF \| TCF7L1 \| SUV420H1 \| CHD8 \| PTEN \| PAK2 \| SVIL \| TLE1 \| MAPK13 \| RPS6KA3
DB_ID:1565	AP-1 transcription factor network	623	18	4.77	3.78	1.92e-06	1.20e-05	ID SCZ
TSC2 \| TBL1XR1 \| TCF3 \| CUL3 \| DGKA \| SMARCC2 \| PRKCA \| TF \| TCF7L1 \| SUV420H1 \| CHD8 \| PTEN \| PAK2 \| SVIL \| TLE1 \| MAPK13 \| RPS6KA3
DB_ID:164	GABA synthesis, release, reuptake and degradation	17	4	0.13	30.75	7.41e-06	4.53e-05	ID
SLC6A1 \| RIMS1 \| STXBP1
DB_ID:11	Developmental Biology	433	14	3.31	4.23	7.67e-06	4.60e-05	ID SCZ
EPHB2 \| ANK2 \| TCF3 \| PAK2 \| ITGB3 \| MYH9 \| CACNA1S \| ROCK1 \| CACNA1D \| MYH10 \| PLXNB1 \| RPS6KA3 \| RGMA
DB_ID:965	Na+/Cl- dependent neurotransmitter transporters	18	4	0.14	29.04	9.46e-06	5.57e-05	-
SLC6A1 \| SLC6A13 \| SLC6A3
DB_ID:1535	Noncanonical Wnt signaling pathway	182	9	1.39	6.46	1.25e-05	7.22e-05	ID SCZ
CHD7 \| TCF7L1 \| TBL1XR1 \| CHD8 \| CUL3 \| SVIL \| TLE1 \| ROCK1
DB_ID:254	Signalling by NGF	143	8	1.09	7.31	1.57e-05	8.90e-05	SCZ
PRKCA \| TSC2 \| PTEN \| PSEN1 \| ADCY5 \| RPS6KA3 \| PIK3R2
DB_ID:863	Deadenylation of mRNA	22	4	0.17	23.76	2.21e-05	0.0001	-
EIF4A1 \| CNOT6 \| CNOT4
DB_ID:1435	Wnt signaling network	200	9	1.53	5.88	2.64e-05	0.0001	ID SCZ
CHD7 \| TCF7L1 \| TBL1XR1 \| CHD8 \| CUL3 \| SVIL \| TLE1 \| ROCK1
DB_ID:18	Sema4D induced cell migration and growth-cone collapse	22	4	0.17	23.76	2.21e-05	0.0001	SCZ
MYH9 \| ROCK1 \| MYH10
DB_ID:289	NGF signalling via TRKA from the plasma membrane	107	7	0.82	8.55	1.95e-05	0.0001	SCZ
PRKCA \| TSC2 \| PTEN \| ADCY5 \| RPS6KA3 \| PIK3R2
DB_ID:937	Transmembrane transport of small molecules	379	12	2.90	4.14	4.18e-05	0.0002	EE
GNAS \| GABRB3 \| SLC7A7 \| ADCY5 \| SLC6A3 \| SLC6A5 \| SLC6A1 \| SLC4A2 \| SLC5A1 \| TF \| ATP10D
DB_ID:331	Signal Transduction	1231	24	9.42	2.55	3.27e-05	0.0002	-
C3 \| TSC2 \| DGKA \| ITGA5 \| LAMC3 \| PRKCA \| PSEN1 \| HRH2 \| PLXNB1 \| GNAS \| DLL1 \| FBN1 \| PTEN \| GRM7 \| ADCY5 \| VIP \| ITGB3 \| PIK3R2 \| OPRL1 \| NOTCH3 \| ROCK1 \| CHRM3 \| RPS6KA3
DB_ID:466	Signaling by PDGF	78	6	0.60	10.05	3.10e-05	0.0002	SCZ
NOTCH3 \| PRKCA \| TSC2 \| PTEN \| ADCY5
DB_ID:16	Sema4D in semaphorin signaling	27	4	0.21	19.36	5.14e-05	0.0002	SCZ
MYH9 \| ROCK1 \| MYH10
DB_ID:1530	Regulation of RAC1 activity	205	9	1.57	5.74	3.20e-05	0.0002	ID
ABI2 \| PTEN \| PAK2 \| TRIO \| CUL3 \| SPATA13 \| ROCK1 \| NCKAP1
DB_ID:1471	Glypican 3 network	206	9	1.58	5.71	3.33e-05	0.0002	ID SCZ
CHD7 \| TCF7L1 \| TBL1XR1 \| CHD8 \| CUL3 \| SVIL \| TLE1 \| ROCK1
DB_ID:1572	RAC1 signaling pathway	205	9	1.57	5.74	3.20e-05	0.0002	ID
ABI2 \| PTEN \| PAK2 \| TRIO \| CUL3 \| SPATA13 \| ROCK1 \| NCKAP1
DB_ID:1650	Regulation of RhoA activity	205	9	1.57	5.74	3.20e-05	0.0002	ID
ABI2 \| PTEN \| PAK2 \| TRIO \| CUL3 \| SPATA13 \| ROCK1 \| NCKAP1
DB_ID:157	Neurotransmitter Release Cycle	26	4	0.20	20.11	4.41e-05	0.0002	ID
SLC6A1 \| RIMS1 \| STXBP1
DB_ID:1647	RhoA signaling pathway	205	9	1.57	5.74	3.20e-05	0.0002	ID
ABI2 \| PTEN \| PAK2 \| TRIO \| CUL3 \| SPATA13 \| ROCK1 \| NCKAP1
DB_ID:646	Amine compound SLC transporters	29	4	0.22	18.03	6.87e-05	0.0003	-
SLC6A1 \| SLC6A13 \| SLC6A3
DB_ID:21	Semaphorin interactions	64	5	0.49	10.21	0.0001	0.0004	SCZ
MYH9 \| ROCK1 \| MYH10 \| PLXNB1
DB_ID:1600	TNF receptor signaling pathway	299	10	2.29	4.37	0.0001	0.0004	ID
TSC2 \| SLK \| TCF3 \| PAK2 \| MADD \| DGKA \| MAPK13 \| APAF1 \| PRKCA
DB_ID:1625	Notch signaling pathway	94	6	0.72	8.34	8.87e-05	0.0004	ID SCZ
TLE1 \| NOTCH3 \| DLL1 \| PSEN1 \| APH1A
DB_ID:1457	Notch-mediated HES/HEY network	94	6	0.72	8.34	8.87e-05	0.0004	ID SCZ
TLE1 \| NOTCH3 \| DLL1 \| PSEN1 \| APH1A
DB_ID:851	Regulation of Insulin Secretion by Acetylcholine	3	2	0.02	87.13	0.0002	0.0008	-
PRKCA
DB_ID:1467	C-MYC pathway	149	7	1.14	6.14	0.0002	0.0008	SCZ
CSDE1 \| CAD \| EIF4A1 \| HSPA4 \| DNMT3A \| TSC2
DB_ID:1542	Canonical Wnt signaling pathway	155	7	1.19	5.90	0.0002	0.0008	ID SCZ
SVIL \| TLE1 \| TCF7L1 \| TBL1XR1 \| CHD8 \| RPS6KA3
DB_ID:634	Metabolism	824	17	6.31	2.70	0.0002	0.0008	SCZ
SUCLA2 \| EIF4A1 \| PRKCA \| SDHA \| CYP4F3 \| ETFB \| CNOT3 \| TPK1 \| GNAS \| CAD \| PAOX \| ADCY5 \| CNOT6 \| CNOT4 \| STXBP1 \| CHRM3
DB_ID:467	Downstream signal transduction	75	5	0.57	8.71	0.0003	0.0011	SCZ
PRKCA \| TSC2 \| PTEN \| ADCY5
DB_ID:1490	Syndecan-3-mediated signaling events	17	3	0.13	23.06	0.0003	0.0011	-
CASK \| PSEN1
DB_ID:161	Reuptake of GABA	4	2	0.03	65.34	0.0003	0.0011	-
SLC6A1
DB_ID:862	Deadenylation-dependent mRNA decay	46	4	0.35	11.36	0.0004	0.0015	-
EIF4A1 \| CNOT6 \| CNOT4
DB_ID:1644	BMP receptor signaling	226	8	1.73	4.63	0.0004	0.0015	-
TSC2 \| TCF3 \| PAK2 \| DGKA \| MAPK13 \| PRKCA \| MEF2C
DB_ID:1621	Presenilin action in Notch and Wnt signaling	46	4	0.35	11.36	0.0004	0.0015	-
TLE1 \| DLL1 \| PSEN1
DB_ID:812	Integration of energy metabolism	83	5	0.64	7.87	0.0005	0.0018	SCZ
GNAS \| PRKCA \| STXBP1 \| ADCY5
DB_ID:450	Signaling by Notch	21	3	0.16	18.67	0.0005	0.0018	-
NOTCH3 \| DLL1
DB_ID:482	G alpha (12/13) signalling events	21	3	0.16	18.67	0.0005	0.0018	-
ROCK1 \| PLXNB1
DB_ID:809	Regulation of Insulin Secretion	48	4	0.37	10.89	0.0005	0.0018	-
GNAS \| PRKCA \| STXBP1
DB_ID:1547	Regulation of nuclear beta catenin signaling and target gene transcription	135	6	1.03	5.81	0.0006	0.0021	ID SCZ
SVIL \| TLE1 \| TCF7L1 \| TBL1XR1 \| CHD8
DB_ID:1549	p38 MAPK signaling pathway	189	7	1.45	4.84	0.0007	0.0024	-
MAPK13 \| PRKCA \| TSC2 \| TCF3 \| PAK2 \| DGKA
DB_ID:64	Hemostasis	376	10	2.88	3.48	0.0007	0.0024	-
GNAS \| PRCP \| EHD2 \| KCNMA1 \| PIK3R2 \| ITGB3 \| DGKA \| ITGA5 \| PRKCA
DB_ID:973	Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds	95	5	0.73	6.88	0.0008	0.0027	ID
SLC6A1 \| SLC5A1 \| SLC6A13 \| SLC6A3
DB_ID:562	Vitamin D (calciferol) metabolism	7	2	0.05	37.34	0.0012	0.0039	-
CUBN
DB_ID:1498	EphrinB-EPHB pathway	60	4	0.46	8.71	0.0012	0.0039	-
ROCK1 \| EPHB2 \| TF
DB_ID:1469	Stabilization and expansion of the E-cadherin adherens junction	275	8	2.10	3.80	0.0014	0.0045	ID SCZ
TCF7L1 \| TBL1XR1 \| CHD8 \| TLE1 \| SVIL \| ROCK1 \| NCKAP1
DB_ID:956	Nephrin interactions	29	3	0.22	13.52	0.0014	0.0045	-
CASK \| KIRREL3
DB_ID:1544	E-cadherin signaling in the nascent adherens junction	275	8	2.10	3.80	0.0014	0.0045	ID SCZ
TCF7L1 \| TBL1XR1 \| CHD8 \| TLE1 \| SVIL \| ROCK1 \| NCKAP1
DB_ID:1617	E-cadherin signaling events	280	8	2.14	3.73	0.0015	0.0047	ID SCZ
TCF7L1 \| TBL1XR1 \| CHD8 \| TLE1 \| SVIL \| ROCK1 \| NCKAP1
DB_ID:241	PI3K/AKT activation	30	3	0.23	13.07	0.0015	0.0047	EE
TSC2 \| PTEN
DB_ID:463	A third proteolytic cleavage releases NICD	8	2	0.06	32.67	0.0016	0.0048	-
NOTCH3
DB_ID:910	Import of palmitoyl-CoA into the mitochondrial matrix	8	2	0.06	32.67	0.0016	0.0048	-
ACACB
DB_ID:446	Notch receptor binds with a ligand	8	2	0.06	32.67	0.0016	0.0048	-
NOTCH3
DB_ID:472	Signaling by SCF-KIT	66	4	0.51	7.92	0.0017	0.0050	-
PRKCA \| TSC2 \| PTEN
DB_ID:325	Downstream signaling of activated FGFR	66	4	0.51	7.92	0.0017	0.0050	SCZ
PRKCA \| TSC2 \| PTEN
DB_ID:1536	Regulation of p38-alpha and p38-beta	164	6	1.25	4.78	0.0017	0.0050	-
PRKCA \| TSC2 \| TCF3 \| PAK2 \| DGKA
DB_ID:1641	Effects of Botulinum toxin	9	2	0.07	29.04	0.0020	0.0057	-
RIMS1
DB_ID:159	Serotonin Neurotransmitter Release Cycle	9	2	0.07	29.04	0.0020	0.0057	-
RIMS1
DB_ID:462	Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor	9	2	0.07	29.04	0.0020	0.0057	-
NOTCH3
DB_ID:155	Dopamine Neurotransmitter Release Cycle	9	2	0.07	29.04	0.0020	0.0057	-
RIMS1
DB_ID:1500	IL1-mediated signaling events	234	7	1.79	3.91	0.0023	0.0064	-
MAPK13 \| PRKCA \| TSC2 \| TCF3 \| PAK2 \| DGKA
DB_ID:530	Integrin cell surface interactions	72	4	0.55	7.26	0.0023	0.0064	-
ITGA5 \| LAMC3 \| FBN1
DB_ID:178	Potassium Channels	76	4	0.58	6.88	0.0028	0.0077	EE ID
KCNC1 \| KCNMA1 \| KCND2
DB_ID:154	Acetylcholine Neurotransmitter Release Cycle	11	2	0.08	23.76	0.0031	0.0083	-
RIMS1
DB_ID:158	Glutamate Neurotransmitter Release Cycle	11	2	0.08	23.76	0.0031	0.0083	-
RIMS1
DB_ID:156	Norepinephrine Neurotransmitter Release Cycle	11	2	0.08	23.76	0.0031	0.0083	-
RIMS1
DB_ID:943	SLC-mediated transmembrane transport	248	7	1.90	3.69	0.0032	0.0084	ID
SLC6A1 \| SLC4A2 \| SLC7A7 \| SLC5A1 \| SLC6A13 \| SLC6A3
DB_ID:44	L1CAM interactions	79	4	0.60	6.62	0.0032	0.0084	ID
EPHB2 \| ANK2 \| RPS6KA3
DB_ID:171	Voltage gated Potassium channels	39	3	0.30	10.05	0.0033	0.0086	EE ID
KCNC1 \| KCND2
DB_ID:1494	N-cadherin signaling events	251	7	1.92	3.64	0.0034	0.0088	ID SCZ
SVIL \| TLE1 \| TCF7L1 \| ROCK1 \| TBL1XR1 \| CHD8
DB_ID:1545	EPHB forward signaling	40	3	0.31	9.80	0.0036	0.0093	-
ROCK1 \| EPHB2
DB_ID:246	ERK/MAPK targets	12	2	0.09	21.78	0.0037	0.0094	-
RPS6KA3
DB_ID:919	Fatty acid, triacylglycerol, and ketone body metabolism	83	4	0.64	6.30	0.0038	0.0096	-
ACACB \| TBL1XR1 \| ELOVL1
DB_ID:984	Metabolism of lipids and lipoproteins	258	7	1.97	3.55	0.0039	0.0098	-
SCP2 \| CUBN \| ACACB \| TBL1XR1 \| ELOVL1 \| CPT2
DB_ID:56	Platelet activation, signaling and aggregation	139	5	1.06	4.70	0.0044	0.0109	-
PRKCA \| TF \| PIK3R2 \| ITGB3
DB_ID:130	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell	89	4	0.68	5.87	0.0049	0.0121	EE ID SCZ
GABRB3 \| ADCY5 \| RPS6KA3
DB_ID:245	Nuclear Events (kinase and transcription factor activation)	15	2	0.11	17.43	0.0057	0.0138	-
RPS6KA3
DB_ID:1475	Validated nuclear estrogen receptor beta network	15	2	0.11	17.43	0.0057	0.0138	-
C3
DB_ID:1660	Alpha6Beta4Integrin	48	3	0.37	8.17	0.0060	0.0145	-
DST \| PRKCA
DB_ID:306	Signaling by FGFR	95	4	0.73	5.50	0.0062	0.0148	SCZ
PRKCA \| TSC2 \| PTEN
DB_ID:1659	Hedgehog	16	2	0.12	16.34	0.0065	0.0152	-
STK36
DB_ID:479	Glucagon-type ligand receptors	16	2	0.12	16.34	0.0065	0.0152	-
GNAS
DB_ID:1438	LPA4-mediated signaling events	16	2	0.12	16.34	0.0065	0.0152	SCZ
GNAS
DB_ID:1524	Signaling mediated by p38-alpha and p38-beta	50	3	0.38	7.84	0.0067	0.0154	-
TSC2 \| TCF3
DB_ID:516	TCR signaling	50	3	0.38	7.84	0.0067	0.0154	-
PTEN \| PAK2
DB_ID:330	Signaling by EGFR	98	4	0.75	5.33	0.0069	0.0158	SCZ
PRKCA \| TSC2 \| PTEN
DB_ID:847	PKA activation in glucagon signalling	17	2	0.13	15.38	0.0074	0.0166	SCZ
GNAS
DB_ID:1501	Caspase cascade in apoptosis	52	3	0.40	7.54	0.0074	0.0166	ID
APAF1 \| SLK
DB_ID:759	Activated AMPK stimulates fatty-acid oxidation in muscle	18	2	0.14	14.52	0.0082	0.0183	-
ACACB
DB_ID:1006	Costimulation by the CD28 family	55	3	0.42	7.13	0.0087	0.0193	-
PDCD1 \| PAK2
DB_ID:1512	Posttranslational regulation of adherens junction stability and dissassembly	231	6	1.77	3.39	0.0090	0.0198	ID SCZ
SVIL \| TLE1 \| TCF7L1 \| TBL1XR1 \| CHD8
DB_ID:872	Citric acid cycle (TCA cycle)	19	2	0.15	13.76	0.0092	0.0201	-
SUCLA2
DB_ID:1611	Regulation of nuclear SMAD2/3 signaling	305	7	2.33	3.00	0.0095	0.0203	SCZ
MAPK13 \| PRKCA \| TSC2 \| TCF3 \| PAK2 \| DGKA
DB_ID:1510	TGF-beta receptor signaling	305	7	2.33	3.00	0.0095	0.0203	SCZ
MAPK13 \| PRKCA \| TSC2 \| TCF3 \| PAK2 \| DGKA
DB_ID:1440	Regulation of cytoplasmic and nuclear SMAD2/3 signaling	305	7	2.33	3.00	0.0095	0.0203	SCZ
MAPK13 \| PRKCA \| TSC2 \| TCF3 \| PAK2 \| DGKA
DB_ID:22	NCAM signaling for neurite out-growth	57	3	0.44	6.88	0.0096	0.0204	-
CACNA1D \| CACNA1S
DB_ID:864	Metabolism of mRNA	235	6	1.80	3.34	0.0098	0.0207	-
EIF4A1 \| CNOT6 \| PRKCA \| CNOT4 \| CNOT3
DB_ID:1107	MAPK targets/ Nuclear events mediated by MAP kinases	21	2	0.16	12.45	0.0111	0.0230	-
RPS6KA3
DB_ID:1458	p38 signaling mediated by MAPKAP kinases	21	2	0.16	12.45	0.0111	0.0230	-
TSC2
DB_ID:302	PIP3 activates AKT signaling	21	2	0.16	12.45	0.0111	0.0230	EE
TSC2
DB_ID:515	Adaptive Immune System	243	6	1.86	3.23	0.0114	0.0234	-
C3 \| PDCD1 \| PTEN \| SEC24D \| PAK2
DB_ID:458	Signaling by GPCR	823	13	6.30	2.06	0.0116	0.0237	-
GNAS \| C3 \| GRM7 \| ADCY5 \| VIP \| PIK3R2 \| DGKA \| OPRL1 \| ROCK1 \| PRKCA \| HRH2 \| CHRM3
DB_ID:1612	ALK1 signaling events	321	7	2.46	2.85	0.0123	0.0246	SCZ
MAPK13 \| PRKCA \| TSC2 \| TCF3 \| PAK2 \| DGKA
DB_ID:484	G alpha (z) signalling events	22	2	0.17	11.88	0.0122	0.0246	SCZ
GNAS
DB_ID:1551	p75(NTR)-mediated signaling	178	5	1.36	3.67	0.0122	0.0246	-
APAF1 \| PRKCA \| PSEN1 \| APH1A
DB_ID:1444	Validated targets of C-MYC transcriptional repression	63	3	0.48	6.22	0.0126	0.0250	-
CSDE1 \| DNMT3A
DB_ID:935	Cell-Cell communication	117	4	0.90	4.47	0.0127	0.0251	-
CASK \| KIRREL3 \| PIK3R2
DB_ID:1583	ALK1 pathway	324	7	2.48	2.82	0.0129	0.0253	SCZ
MAPK13 \| PRKCA \| TSC2 \| TCF3 \| PAK2 \| DGKA
DB_ID:116	NCAM1 interactions	23	2	0.18	11.36	0.0133	0.0259	SCZ
CACNA1D
DB_ID:981	Regulation of Water Balance by Renal Aquaporins	24	2	0.18	10.89	0.0144	0.0274	SCZ
GNAS
DB_ID:28	CDO in myogenesis	24	2	0.18	10.89	0.0144	0.0274	-
TCF3
DB_ID:1623	Regulation of retinoblastoma protein	66	3	0.51	5.94	0.0142	0.0274	ID
SFTPD \| CBX4
DB_ID:29	Myogenesis	24	2	0.18	10.89	0.0144	0.0274	-
TCF3
DB_ID:338	Calmodulin induced events	25	2	0.19	10.46	0.0156	0.0291	SCZ
PRKCA
DB_ID:1070	Steroid hormones	25	2	0.19	10.46	0.0156	0.0291	-
CUBN
DB_ID:339	CaM pathway	25	2	0.19	10.46	0.0156	0.0291	SCZ
PRKCA
DB_ID:459	GPCR ligand binding	338	7	2.59	2.71	0.0159	0.0295	-
GNAS \| C3 \| OPRL1 \| GRM7 \| VIP \| HRH2
DB_ID:323	Phospholipase C-mediated cascade	27	2	0.21	9.68	0.0181	0.0322	SCZ
PRKCA
DB_ID:493	Ca-dependent events	27	2	0.21	9.68	0.0181	0.0322	SCZ
PRKCA
DB_ID:336	DAG and IP3 signaling	27	2	0.21	9.68	0.0181	0.0322	SCZ
PRKCA
DB_ID:68	Cell surface interactions at the vascular wall	72	3	0.55	5.45	0.0180	0.0322	-
ITGA5 \| PIK3R2
DB_ID:321	PI-3K cascade	27	2	0.21	9.68	0.0181	0.0322	EE
TSC2
DB_ID:992	Aquaporin-mediated transport	27	2	0.21	9.68	0.0181	0.0322	SCZ
GNAS
DB_ID:1559	FAS (CD95) signaling pathway	130	4	0.99	4.02	0.0180	0.0322	ID
APAF1 \| PRKCA \| SLK
DB_ID:166	CREB phosphorylation through the activation of Ras	28	2	0.21	9.33	0.0194	0.0343	ID
RPS6KA3
DB_ID:1523	Reelin signaling pathway	29	2	0.22	9.01	0.0207	0.0362	ID SCZ
RELN
DB_ID:337	EGFR interacts with phospholipase C-gamma	29	2	0.22	9.01	0.0207	0.0362	SCZ
PRKCA
DB_ID:1581	Syndecan-2-mediated signaling events	77	3	0.59	5.09	0.0214	0.0372	-
ITGA5 \| CASK
DB_ID:240	PLC-gamma1 signalling	30	2	0.23	8.71	0.0221	0.0374	SCZ
PRKCA
DB_ID:1108	MAP kinase activation in TLR cascade	30	2	0.23	8.71	0.0221	0.0374	-
RPS6KA3
DB_ID:865	Metabolism of RNA	282	6	2.16	2.78	0.0221	0.0374	-
EIF4A1 \| CNOT6 \| PRKCA \| CNOT4 \| CNOT3
DB_ID:1548	Ephrin B reverse signaling	30	2	0.23	8.71	0.0221	0.0374	-
EPHB2
DB_ID:1664	EGFR1	138	4	1.06	3.79	0.0219	0.0374	SCZ
KRT7 \| PRKCA \| RPS6KA3
DB_ID:522	Immune System	532	9	4.07	2.21	0.0223	0.0375	ID SCZ
C3 \| PDCD1 \| PTEN \| SEC24D \| PAK2 \| PIK3R2 \| ITGB3 \| RPS6KA3
DB_ID:1484	Lissencephaly gene (LIS1) in neuronal migration and development	31	2	0.24	8.43	0.0235	0.0389	-
RELN
DB_ID:476	G alpha (s) signalling events	31	2	0.24	8.43	0.0235	0.0389	SCZ
GNAS
DB_ID:546	Pyruvate metabolism and Citric Acid (TCA) cycle	31	2	0.24	8.43	0.0235	0.0389	-
SUCLA2
DB_ID:1493	Validated targets of C-MYC transcriptional activation	81	3	0.62	4.84	0.0244	0.0399	ID SCZ
CAD \| EIF4A1
DB_ID:308	GAB1 signalosome	32	2	0.24	8.17	0.0249	0.0399	EE
TSC2
DB_ID:43	Recycling pathway of L1	32	2	0.24	8.17	0.0249	0.0399	-
RPS6KA3
DB_ID:576	Metabolism of steroid hormones and vitamins A and D	32	2	0.24	8.17	0.0249	0.0399	-
CUBN
DB_ID:580	Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)	32	2	0.24	8.17	0.0249	0.0399	-
TBL1XR1
DB_ID:475	G alpha (i) signalling events	32	2	0.24	8.17	0.0249	0.0399	SCZ
GNAS
DB_ID:846	Glucagon signaling in metabolic regulation	33	2	0.25	7.92	0.0264	0.0421	SCZ
GNAS
DB_ID:1024	RNA Polymerase III Abortive And Retractive Initiation	34	2	0.26	7.69	0.0279	0.0431	-
SNAPC5
DB_ID:1560	C-MYB transcription factor network	85	3	0.65	4.61	0.0277	0.0431	-
SND1 \| PAX5
DB_ID:1023	RNA Polymerase III Transcription	34	2	0.26	7.69	0.0279	0.0431	-
SNAPC5
DB_ID:140	Activation of NMDA receptor upon glutamate binding and postsynaptic events	34	2	0.26	7.69	0.0279	0.0431	ID SCZ
RPS6KA3
DB_ID:1569	Glucocorticoid receptor signaling	85	3	0.65	4.61	0.0277	0.0431	SCZ
GNAS \| SUV420H1
DB_ID:142	Post NMDA receptor activation events	34	2	0.26	7.69	0.0279	0.0431	ID SCZ
RPS6KA3
DB_ID:27	Signal transduction by L1	35	2	0.27	7.47	0.0294	0.0450	-
ANK2
DB_ID:1005	Downstream TCR signaling	35	2	0.27	7.47	0.0294	0.0450	-
PTEN
DB_ID:495	Amine ligand-binding receptors	36	2	0.28	7.26	0.0310	0.0467	-
HRH2
DB_ID:1000	CD28 co-stimulation	36	2	0.28	7.26	0.0310	0.0467	-
PAK2
DB_ID:192	GABA receptor activation	36	2	0.28	7.26	0.0310	0.0467	EE SCZ
GABRB3 \| ADCY5

Wikipathways pathway

wiki accession	wiki pathway name	Number of reference genes	Number of genes	Expected number	Ratio of entrichment	Raw P_Value	Adjusted P_Value	Other disease
DB_ID:141	Unblocking of NMDA receptor, glutamate binding and activation	11	4	0.03	147.95	1.12e-08	1.76e-06	-
DLG4 \| GRIN2A \| CAMK2G
DB_ID:143	Neuronal System	188	8	0.46	17.31	2.35e-08	1.84e-06	EE ASD SCZ
KCNQ3 \| KCNA1 \| DLG4 \| SLC6A1 \| GRIN2A \| STXBP1 \| CAMK2G
DB_ID:197	CREB phosphorylation through the activation of CaMKII	15	4	0.04	108.50	4.61e-08	2.41e-06	-
DLG4 \| GRIN2A \| CAMK2G
DB_ID:167	Ras activation uopn Ca2+ infux through NMDA receptor	17	4	0.04	95.73	8.00e-08	3.14e-06	-
DLG4 \| GRIN2A \| CAMK2G
DB_ID:1573	ErbB receptor signaling network	1312	15	3.22	4.65	7.95e-07	1.56e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DLG4 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G \| GRIN2B
DB_ID:150	Transmission across Chemical Synapses	121	6	0.30	20.17	5.84e-07	1.56e-05	EE ASD SCZ
SLC6A1 \| DLG4 \| GRIN2A \| STXBP1 \| CAMK2G
DB_ID:1662	TGFBR	125	6	0.31	19.53	7.07e-07	1.56e-05	SCZ
CTCF \| RB1 \| CTNNB1 \| SMAD6 \| RBL2
DB_ID:166	CREB phosphorylation through the activation of Ras	28	4	0.07	58.12	6.74e-07	1.56e-05	ASD
DLG4 \| GRIN2A \| CAMK2G
DB_ID:140	Activation of NMDA receptor upon glutamate binding and postsynaptic events	34	4	0.08	47.87	1.51e-06	2.37e-05	ASD SCZ
DLG4 \| GRIN2A \| CAMK2G
DB_ID:142	Post NMDA receptor activation events	34	4	0.08	47.87	1.51e-06	2.37e-05	ASD SCZ
DLG4 \| GRIN2A \| CAMK2G
DB_ID:1037	Apoptotic cleavage of cell adhesion proteins	12	3	0.03	101.71	3.12e-06	4.45e-05	-
CTNNB1 \| DSP
DB_ID:1480	TRAIL signaling pathway	1328	14	3.26	4.29	4.86e-06	6.36e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G \| MAP3K1
DB_ID:1564	IL3-mediated signaling events	1295	13	3.18	4.08	1.82e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1575	VEGF and VEGFR signaling network	1304	13	3.21	4.06	1.96e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1619	Endothelins	1307	13	3.21	4.05	2.01e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1603	EGFR-dependent Endothelin signaling events	1289	13	3.17	4.10	1.74e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1553	Class I PI3K signaling events	1288	13	3.17	4.11	1.72e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1497	PDGF receptor signaling network	1293	13	3.18	4.09	1.79e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1578	Alpha9 beta1 integrin signaling events	1305	13	3.21	4.05	1.97e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1519	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling	1288	13	3.17	4.11	1.72e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1491	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)	1293	13	3.18	4.09	1.79e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1540	PDGFR-beta signaling pathway	1288	13	3.17	4.11	1.72e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1649	LKB1 signaling events	1308	13	3.21	4.04	2.02e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1516	Signaling events mediated by VEGFR1 and VEGFR2	1296	13	3.19	4.08	1.84e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1602	ErbB1 downstream signaling	1288	13	3.17	4.11	1.72e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1482	IGF1 pathway	1291	13	3.17	4.10	1.76e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1556	Plasma membrane estrogen receptor signaling	1301	13	3.20	4.07	1.91e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1552	Thrombin/protease-activated receptor (PAR) pathway	1300	13	3.20	4.07	1.90e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1615	Arf6 trafficking events	1288	13	3.17	4.11	1.72e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1509	Internalization of ErbB1	1288	13	3.17	4.11	1.72e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1550	EGF receptor (ErbB1) signaling pathway	1288	13	3.17	4.11	1.72e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1472	Nectin adhesion pathway	1295	13	3.18	4.08	1.82e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1529	IFN-gamma pathway	1296	13	3.19	4.08	1.84e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1571	mTOR signaling pathway	1288	13	3.17	4.11	1.72e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1585	Arf6 downstream pathway	1288	13	3.17	4.11	1.72e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1454	Syndecan-1-mediated signaling events	1300	13	3.20	4.07	1.90e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1648	Class I PI3K signaling events mediated by Akt	1288	13	3.17	4.11	1.72e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1466	Insulin Pathway	1288	13	3.17	4.11	1.72e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1554	Arf6 signaling events	1288	13	3.17	4.11	1.72e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:389	Cell Cycle, Mitotic	318	7	0.78	8.96	1.45e-05	6.89e-05	-
DYNC1H1 \| RB1 \| TUBA1A \| STAG1 \| RBL2 \| PSMA7
DB_ID:1492	Glypican 1 network	1299	13	3.19	4.07	1.88e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1531	PAR1-mediated thrombin signaling events	1299	13	3.19	4.07	1.88e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1461	GMCSF-mediated signaling events	1292	13	3.18	4.09	1.78e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1627	IL5-mediated signaling events	1292	13	3.18	4.09	1.78e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1574	Signaling events mediated by focal adhesion kinase	1288	13	3.17	4.11	1.72e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1594	S1P1 pathway	1288	13	3.17	4.11	1.72e-05	6.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1635	Sphingosine 1-phosphate (S1P) pathway	1311	13	3.22	4.03	2.07e-05	6.91e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1459	Glypican pathway	1338	13	3.29	3.95	2.56e-05	8.37e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1637	Proteoglycan syndecan-mediated signaling events	1345	13	3.31	3.93	2.70e-05	8.65e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1517	Beta1 integrin cell surface interactions	1351	13	3.32	3.91	2.83e-05	8.89e-05	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:1499	Integrin family cell surface interactions	1378	13	3.39	3.84	3.47e-05	0.0001	ASD SCZ
UBTF \| RB1 \| RAPGEF1 \| CTNNB1 \| TCF4 \| SLC2A1 \| LRP1 \| DSP \| RBL2 \| SMAD6 \| KDM1A \| CAMK2G
DB_ID:99	DNA Replication	261	6	0.64	9.35	4.77e-05	0.0001	-
DYNC1H1 \| RB1 \| TUBA1A \| STAG1 \| PSMA7
DB_ID:1523	Reelin signaling pathway	29	3	0.07	42.09	5.03e-05	0.0001	ASD SCZ
RAPGEF1 \| GRIN2A
DB_ID:130	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell	89	4	0.22	18.29	7.17e-05	0.0002	EE ASD SCZ
DLG4 \| GRIN2A \| CAMK2G
DB_ID:1657	Wnt	82	4	0.20	19.85	5.20e-05	0.0002	SCZ
DLG4 \| CTNNB1 \| CAMK2G
DB_ID:1035	Apoptotic cleavage of cellular proteins	39	3	0.10	31.30	0.0001	0.0003	-
CTNNB1 \| DSP
DB_ID:1040	Apoptotic execution phase	48	3	0.12	25.43	0.0002	0.0006	-
CTNNB1 \| DSP
DB_ID:96	Mitotic M-M/G1 phases	242	5	0.59	8.41	0.0003	0.0008	-
DYNC1H1 \| TUBA1A \| STAG1 \| PSMA7
DB_ID:1494	N-cadherin signaling events	251	5	0.62	8.10	0.0004	0.0011	ASD SCZ
CTNNB1 \| DSP \| TCF4 \| CAMK2G
DB_ID:1506	Coregulation of Androgen receptor activity	61	3	0.15	20.01	0.0005	0.0013	-
CTNNB1 \| TCF4
DB_ID:1544	E-cadherin signaling in the nascent adherens junction	275	5	0.68	7.40	0.0006	0.0015	ASD SCZ
RAPGEF1 \| CTNNB1 \| DSP \| TCF4
DB_ID:1068	Apoptosis	158	4	0.39	10.30	0.0006	0.0015	-
CTNNB1 \| DSP \| PSMA7
DB_ID:1469	Stabilization and expansion of the E-cadherin adherens junction	275	5	0.68	7.40	0.0006	0.0015	ASD SCZ
RAPGEF1 \| CTNNB1 \| DSP \| TCF4
DB_ID:97	M Phase	158	4	0.39	10.30	0.0006	0.0015	-
DYNC1H1 \| TUBA1A \| STAG1
DB_ID:11	Developmental Biology	433	6	1.06	5.64	0.0007	0.0017	ASD SCZ
DLG4 \| MED13L \| MYH9 \| CTNNB1 \| CAP1
DB_ID:1617	E-cadherin signaling events	280	5	0.69	7.27	0.0007	0.0017	ASD SCZ
RAPGEF1 \| CTNNB1 \| DSP \| TCF4
DB_ID:164	GABA synthesis, release, reuptake and degradation	17	2	0.04	47.87	0.0008	0.0019	ASD
SLC6A1
DB_ID:1546	Integrin-linked kinase signaling	656	7	1.61	4.34	0.0012	0.0027	ASD SCZ
RB1 \| CTNNB1 \| TCF4 \| ELMO2 \| KDM1A \| SLC2A1
DB_ID:137	Trafficking of AMPA receptors	21	2	0.05	38.75	0.0012	0.0027	-
DLG4
DB_ID:136	Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity	21	2	0.05	38.75	0.0012	0.0027	-
DLG4
DB_ID:91	Mitotic Metaphase/Anaphase Transition	22	2	0.05	36.99	0.0013	0.0029	-
STAG1
DB_ID:1572	RAC1 signaling pathway	205	4	0.50	7.94	0.0017	0.0036	ASD
RB1 \| CTNNB1 \| NGEF
DB_ID:1530	Regulation of RAC1 activity	205	4	0.50	7.94	0.0017	0.0036	ASD
RB1 \| CTNNB1 \| NGEF
DB_ID:1650	Regulation of RhoA activity	205	4	0.50	7.94	0.0017	0.0036	ASD
RB1 \| CTNNB1 \| NGEF
DB_ID:1647	RhoA signaling pathway	205	4	0.50	7.94	0.0017	0.0036	ASD
RB1 \| CTNNB1 \| NGEF
DB_ID:157	Neurotransmitter Release Cycle	26	2	0.06	31.30	0.0019	0.0039	ASD
SLC6A1
DB_ID:20	Axon guidance	219	4	0.54	7.43	0.0021	0.0043	ASD SCZ
DLG4 \| MYH9 \| CAP1
DB_ID:1636	Regulation of Androgen receptor activity	108	3	0.27	11.30	0.0024	0.0048	SCZ
CTNNB1 \| TCF4
DB_ID:384	G1 Phase	31	2	0.08	26.25	0.0027	0.0052	-
RB1
DB_ID:1488	CDC42 signaling events	757	7	1.86	3.76	0.0027	0.0052	ASD SCZ
RB1 \| CTNNB1 \| TCF4 \| KDM1A \| SLC2A1 \| NGEF
DB_ID:394	Cyclin D associated events in G1	31	2	0.08	26.25	0.0027	0.0052	-
RB1
DB_ID:1512	Posttranslational regulation of adherens junction stability and dissassembly	231	4	0.57	7.05	0.0026	0.0052	ASD SCZ
CTNNB1 \| DSP \| TCF4
DB_ID:1584	ErbB4 signaling events	32	2	0.08	25.43	0.0028	0.0053	-
DLG4
DB_ID:1456	Regulation of CDC42 activity	770	7	1.89	3.70	0.0030	0.0056	ASD SCZ
RB1 \| CTNNB1 \| TCF4 \| KDM1A \| SLC2A1 \| NGEF
DB_ID:1618	Androgen-mediated signaling	130	3	0.32	9.39	0.0041	0.0075	SCZ
CTNNB1 \| TCF4
DB_ID:1559	FAS (CD95) signaling pathway	130	3	0.32	9.39	0.0041	0.0075	ASD
RB1 \| MAP3K1
DB_ID:171	Voltage gated Potassium channels	39	2	0.10	20.86	0.0042	0.0076	EE ASD
KCNQ3
DB_ID:1565	AP-1 transcription factor network	623	6	1.53	3.92	0.0045	0.0080	ASD SCZ
RB1 \| CTNNB1 \| TCF4 \| KDM1A \| SLC2A1
DB_ID:1547	Regulation of nuclear beta catenin signaling and target gene transcription	135	3	0.33	9.04	0.0046	0.0081	ASD SCZ
CTNNB1 \| TCF4
DB_ID:388	Mitotic G1-G1/S phases	141	3	0.35	8.66	0.0052	0.0091	-
RB1 \| RBL2
DB_ID:756	Meiotic Synapsis	47	2	0.12	17.31	0.0060	0.0104	SCZ
STAG1
DB_ID:1522	Ceramide signaling pathway	49	2	0.12	16.61	0.0065	0.0110	-
RB1
DB_ID:1557	FoxO family signaling	49	2	0.12	16.61	0.0065	0.0110	EE
CTNNB1
DB_ID:1542	Canonical Wnt signaling pathway	155	3	0.38	7.87	0.0067	0.0112	ASD SCZ
CTNNB1 \| TCF4
DB_ID:1501	Caspase cascade in apoptosis	52	2	0.13	15.65	0.0073	0.0121	ASD
MAP3K1
DB_ID:351	Loss of Nlp from mitotic centrosomes	61	2	0.15	13.34	0.0100	0.0162	-
DYNC1H1
DB_ID:354	Loss of proteins required for interphase microtubule organizationÃÂ from the centrosome	61	2	0.15	13.34	0.0100	0.0162	-
DYNC1H1
DB_ID:1535	Noncanonical Wnt signaling pathway	182	3	0.45	6.71	0.0104	0.0163	ASD SCZ
CTNNB1 \| TCF4
DB_ID:94	Mitotic Prophase	62	2	0.15	13.12	0.0103	0.0163	-
DYNC1H1
DB_ID:95	Golgi Cisternae Pericentriolar Stack Reorganization	62	2	0.15	13.12	0.0103	0.0163	-
DYNC1H1
DB_ID:1623	Regulation of retinoblastoma protein	66	2	0.16	12.33	0.0116	0.0180	ASD
UBTF
DB_ID:1513	BCR signaling pathway	67	2	0.16	12.15	0.0119	0.0183	-
CAMK2G
DB_ID:372	Centrosome maturation	70	2	0.17	11.62	0.0130	0.0196	-
DYNC1H1
DB_ID:371	Recruitment of mitotic centrosome proteins and complexes	70	2	0.17	11.62	0.0130	0.0196	-
DYNC1H1
DB_ID:1435	Wnt signaling network	200	3	0.49	6.10	0.0134	0.0200	ASD SCZ
CTNNB1 \| TCF4
DB_ID:758	Meiosis	72	2	0.18	11.30	0.0137	0.0203	SCZ
STAG1
DB_ID:1626	E2F transcription factor network	73	2	0.18	11.15	0.0140	0.0205	-
RB1
DB_ID:527	Signaling by Wnt	75	2	0.18	10.85	0.0148	0.0211	-
CTNNB1
DB_ID:528	Degradation of beta-catenin by the destruction complex	75	2	0.18	10.85	0.0148	0.0211	-
CTNNB1
DB_ID:1471	Glypican 3 network	206	3	0.51	5.93	0.0145	0.0211	ASD SCZ
CTNNB1 \| TCF4
DB_ID:1604	Syndecan-4-mediated signaling events	209	3	0.51	5.84	0.0150	0.0212	ASD SCZ
CTNNB1 \| TCF4
DB_ID:178	Potassium Channels	76	2	0.19	10.71	0.0152	0.0213	EE ASD
KCNQ3
DB_ID:684	Asparagine N-linked glycosylation	77	2	0.19	10.57	0.0155	0.0215	-
TUSC3
DB_ID:380	Cyclin E associated events during G1/S transition	78	2	0.19	10.43	0.0159	0.0215	-
RB1
DB_ID:1656	AndrogenReceptor	78	2	0.19	10.43	0.0159	0.0215	-
RB1
DB_ID:1561	p73 transcription factor network	78	2	0.19	10.43	0.0159	0.0215	-
RB1
DB_ID:44	L1CAM interactions	79	2	0.19	10.30	0.0163	0.0219	ASD
DLG4
DB_ID:1493	Validated targets of C-MYC transcriptional activation	81	2	0.20	10.05	0.0171	0.0228	ASD SCZ
UBTF
DB_ID:439	Switching of origins to a post-replicative state	83	2	0.20	9.80	0.0179	0.0234	-
RB1
DB_ID:440	Orc1 removal from chromatin	83	2	0.20	9.80	0.0179	0.0234	-
RB1
DB_ID:431	Removal of licensing factors from origins	85	2	0.21	9.57	0.0187	0.0243	-
RB1
DB_ID:433	Regulation of DNA replication	88	2	0.22	9.25	0.0200	0.0257	-
RB1
DB_ID:383	Cyclin A:Cdk2-associated events at S phase entry	90	2	0.22	9.04	0.0208	0.0265	-
RB1
DB_ID:1625	Notch signaling pathway	94	2	0.23	8.66	0.0226	0.0284	ASD SCZ
RB1
DB_ID:1457	Notch-mediated HES/HEY network	94	2	0.23	8.66	0.0226	0.0284	ASD SCZ
RB1
DB_ID:973	Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds	95	2	0.23	8.57	0.0230	0.0287	ASD
SLC6A1
DB_ID:366	G2/M Transition	96	2	0.24	8.48	0.0235	0.0288	-
DYNC1H1
DB_ID:943	SLC-mediated transmembrane transport	248	3	0.61	4.92	0.0235	0.0288	ASD
SLC6A1 \| SLC26A9
DB_ID:364	Mitotic G2-G2/M phases	99	2	0.24	8.22	0.0249	0.0301	-
DYNC1H1
DB_ID:93	Mitotic Prometaphase	99	2	0.24	8.22	0.0249	0.0301	-
STAG1
DB_ID:1476	Neurotrophic factor-mediated Trk receptor signaling	101	2	0.25	8.06	0.0258	0.0309	-
RAPGEF1
DB_ID:437	Synthesis of DNA	109	2	0.27	7.47	0.0297	0.0353	-
RB1
DB_ID:702	Post-translational protein modification	114	2	0.28	7.14	0.0322	0.0380	-
TUSC3
DB_ID:381	G1/S Transition	118	2	0.29	6.90	0.0343	0.0402	-
RB1
DB_ID:382	S Phase	121	2	0.30	6.72	0.0360	0.0419	-
RB1
DB_ID:1600	TNF receptor signaling pathway	299	3	0.73	4.08	0.0378	0.0436	ASD
RB1 \| MAP3K1
DB_ID:1599	ATM pathway	307	3	0.75	3.98	0.0403	0.0462	SCZ
RB1 \| RBL2
DB_ID:522	Immune System	532	4	1.31	3.06	0.0426	0.0485	ASD SCZ
RAPGEF1 \| PSMA7 \| MAP3K1 \| SPTAN1

Wikipathways pathway

wiki accession	wiki pathway name	Number of reference genes	Number of genes	Expected number	Ratio of entrichment	Raw P_Value	Adjusted P_Value	Other disease
DB_ID:143	Neuronal System	188	8	0.48	16.84	2.93e-08	3.81e-06	ID ASD SCZ
KCNQ2 \| GABRB1 \| KCNB1 \| GABRB3 \| KCNQ3 \| STXBP1 \| KCNH5
DB_ID:171	Voltage gated Potassium channels	39	4	0.10	40.58	2.97e-06	0.0002	ID ASD
KCNQ2 \| KCNB1 \| KCNQ3
DB_ID:178	Potassium Channels	76	4	0.19	20.82	4.31e-05	0.0019	ID ASD
KCNQ2 \| KCNB1 \| KCNQ3
DB_ID:187	GABA A receptor activation	5	2	0.01	158.26	6.30e-05	0.0020	-
GABRB1
DB_ID:978	Ion channel transport	46	3	0.12	25.80	0.0002	0.0052	-
GABRB1 \| GABRB3
DB_ID:1570	Hedgehog signaling events mediated by Gli proteins	48	3	0.12	24.73	0.0003	0.0056	-
IFT172 \| GNAO1
DB_ID:150	Transmission across Chemical Synapses	121	4	0.31	13.08	0.0003	0.0056	ID ASD SCZ
GABRB1 \| GABRB3 \| STXBP1
DB_ID:1446	Signaling events mediated by the Hedgehog family	65	3	0.16	18.26	0.0006	0.0097	-
IFT172 \| GNAO1
DB_ID:985	Ligand-gated ion channel transport	17	2	0.04	46.55	0.0008	0.0116	-
GABRB1
DB_ID:130	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell	89	3	0.22	13.34	0.0015	0.0163	ID ASD SCZ
GABRB1 \| GABRB3
DB_ID:1593	CXCR4-mediated signaling events	192	4	0.49	8.24	0.0015	0.0163	SCZ
FLNA \| PTEN \| MTOR
DB_ID:302	PIP3 activates AKT signaling	21	2	0.05	37.68	0.0013	0.0163	ASD
PTEN
DB_ID:321	PI-3K cascade	27	2	0.07	29.31	0.0021	0.0210	ASD
PTEN
DB_ID:71	Platelet degranulation	29	2	0.07	27.29	0.0025	0.0225	-
TTN
DB_ID:241	PI3K/AKT activation	30	2	0.08	26.38	0.0026	0.0225	ASD
PTEN
DB_ID:937	Transmembrane transport of small molecules	379	5	0.96	5.22	0.0028	0.0227	ASD
GABRB1 \| GABRB3 \| SLC35A2 \| ATP2B4
DB_ID:308	GAB1 signalosome	32	2	0.08	24.73	0.0030	0.0229	ASD
PTEN
DB_ID:192	GABA receptor activation	36	2	0.09	21.98	0.0038	0.0274	ASD SCZ
GABRB1
DB_ID:1437	CXCR3-mediated signaling events	37	2	0.09	21.39	0.0040	0.0274	-
MTOR
DB_ID:73	Response to elevated platelet cytosolic Ca2+	40	2	0.10	19.78	0.0046	0.0299	-
TTN
DB_ID:1557	FoxO family signaling	49	2	0.12	16.15	0.0069	0.0427	ID
CSNK1E \| YWHAG

Wikipathways pathway

wiki accession	wiki pathway name	Number of reference genes	Number of genes	Expected number	Ratio of entrichment	Raw P_Value	Adjusted P_Value	Other disease
DB_ID:1517	Beta1 integrin cell surface interactions	1351	37	8.71	4.25	1.54e-13	3.57e-11	ID ASD
MAPK8 \| SMAD7 \| CAMK4 \| BCAT1 \| COL3A1 \| ICAM1 \| ASAP2 \| ASAP1 \| HUWE1 \| CHD8 \| PYCARD \| ACTA2 \| HSP90AA1 \| TGM2 \| ITSN1 \| NOS3 \| ADCY7 \| COL6A2 \| RB1CC1 \| HSPA8 \| CUL3 \| LRP1 \| ACTN1 \| RUNX3 \| CD14 \| LAMA2 \| SMARCC2 \| NUP214 \| BLNK \| KPNA1 \| TRRAP \| EPHA2 \| HIF1A \| GNAO1 \| PML \| PTK2B
DB_ID:1499	Integrin family cell surface interactions	1378	37	8.88	4.17	2.78e-13	3.57e-11	ID ASD
MAPK8 \| SMAD7 \| CAMK4 \| BCAT1 \| COL3A1 \| ICAM1 \| ASAP2 \| ASAP1 \| HUWE1 \| CHD8 \| PYCARD \| ACTA2 \| HSP90AA1 \| TGM2 \| ITSN1 \| NOS3 \| ADCY7 \| COL6A2 \| RB1CC1 \| HSPA8 \| CUL3 \| LRP1 \| ACTN1 \| RUNX3 \| CD14 \| LAMA2 \| SMARCC2 \| NUP214 \| BLNK \| KPNA1 \| TRRAP \| EPHA2 \| HIF1A \| GNAO1 \| PML \| PTK2B
DB_ID:1619	Endothelins	1307	34	8.43	4.04	6.60e-12	4.33e-10	ID ASD
MAPK8 \| SMAD7 \| CAMK4 \| BCAT1 \| COL3A1 \| ICAM1 \| ASAP2 \| ASAP1 \| HUWE1 \| CHD8 \| PYCARD \| ADCY9 \| ACTA2 \| HSP90AA1 \| ITSN1 \| NOS3 \| ADCY7 \| RB1CC1 \| HSPA8 \| CUL3 \| LRP1 \| ACTN1 \| RUNX3 \| SMARCC2 \| NUP214 \| BLNK \| TRRAP \| KPNA1 \| EPHA2 \| HIF1A \| GNAO1 \| PML \| PTK2B
DB_ID:1649	LKB1 signaling events	1308	34	8.43	4.03	6.74e-12	4.33e-10	ID ASD
MAPK8 \| SMAD7 \| CAMK4 \| BCAT1 \| ICAM1 \| MARK4 \| ASAP2 \| ASAP1 \| HUWE1 \| CHD8 \| BRSK1 \| PYCARD \| ACTA2 \| HSP90AA1 \| ITSN1 \| NOS3 \| ADCY7 \| RB1CC1 \| HSPA8 \| CUL3 \| LRP1 \| ACTN1 \| RUNX3 \| SMARCC2 \| NUP214 \| BLNK \| TRRAP \| KPNA1 \| EPHA2 \| HIF1A \| GNAO1 \| PML \| PTK2B
DB_ID:1459	Glypican pathway	1338	34	8.62	3.94	1.24e-11	6.37e-10	ID ASD
MAPK8 \| SMAD7 \| CAMK4 \| BCAT1 \| ICAM1 \| ASAP2 \| ASAP1 \| HUWE1 \| CHD8 \| PYCARD \| ACTA2 \| HSP90AA1 \| SLIT2 \| ITSN1 \| NOS3 \| ADCY7 \| RB1CC1 \| HSPA8 \| CUL3 \| LRP1 \| LRP5 \| ACTN1 \| RUNX3 \| SMARCC2 \| NUP214 \| BLNK \| TRRAP \| KPNA1 \| EPHA2 \| HIF1A \| GNAO1 \| PML \| PTK2B
DB_ID:1492	Glypican 1 network	1299	33	8.37	3.94	2.57e-11	7.45e-10	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| SLIT2 \| ITSN1 \| NOS3
DB_ID:1578	Alpha9 beta1 integrin signaling events	1305	33	8.41	3.92	2.90e-11	7.45e-10	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| TGM2 \| ITSN1 \| NOS3
DB_ID:1575	VEGF and VEGFR signaling network	1304	33	8.41	3.93	2.84e-11	7.45e-10	ID ASD
MAPK8 \| MYOF \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1516	Signaling events mediated by VEGFR1 and VEGFR2	1296	33	8.35	3.95	2.42e-11	7.45e-10	ID ASD
MAPK8 \| MYOF \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1556	Plasma membrane estrogen receptor signaling	1301	33	8.39	3.93	2.68e-11	7.45e-10	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| ESR2 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1519	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling	1288	32	8.30	3.85	9.24e-11	8.13e-10	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1491	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)	1293	32	8.33	3.84	1.02e-10	8.13e-10	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1550	EGF receptor (ErbB1) signaling pathway	1288	32	8.30	3.85	9.24e-11	8.13e-10	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1615	Arf6 trafficking events	1288	32	8.30	3.85	9.24e-11	8.13e-10	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1466	Insulin Pathway	1288	32	8.30	3.85	9.24e-11	8.13e-10	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1602	ErbB1 downstream signaling	1288	32	8.30	3.85	9.24e-11	8.13e-10	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1594	S1P1 pathway	1288	32	8.30	3.85	9.24e-11	8.13e-10	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1552	Thrombin/protease-activated receptor (PAR) pathway	1300	32	8.38	3.82	1.17e-10	8.13e-10	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1553	Class I PI3K signaling events	1288	32	8.30	3.85	9.24e-11	8.13e-10	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1461	GMCSF-mediated signaling events	1292	32	8.33	3.84	9.98e-11	8.13e-10	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1472	Nectin adhesion pathway	1295	32	8.35	3.83	1.06e-10	8.13e-10	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1627	IL5-mediated signaling events	1292	32	8.33	3.84	9.98e-11	8.13e-10	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1509	Internalization of ErbB1	1288	32	8.30	3.85	9.24e-11	8.13e-10	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1554	Arf6 signaling events	1288	32	8.30	3.85	9.24e-11	8.13e-10	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1574	Signaling events mediated by focal adhesion kinase	1288	32	8.30	3.85	9.24e-11	8.13e-10	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1529	IFN-gamma pathway	1296	32	8.35	3.83	1.08e-10	8.13e-10	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1564	IL3-mediated signaling events	1295	32	8.35	3.83	1.06e-10	8.13e-10	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1571	mTOR signaling pathway	1288	32	8.30	3.85	9.24e-11	8.13e-10	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1585	Arf6 downstream pathway	1288	32	8.30	3.85	9.24e-11	8.13e-10	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1540	PDGFR-beta signaling pathway	1288	32	8.30	3.85	9.24e-11	8.13e-10	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1497	PDGF receptor signaling network	1293	32	8.33	3.84	1.02e-10	8.13e-10	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1531	PAR1-mediated thrombin signaling events	1299	32	8.37	3.82	1.14e-10	8.13e-10	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1637	Proteoglycan syndecan-mediated signaling events	1345	33	8.67	3.81	6.34e-11	8.13e-10	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| NCAN \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1482	IGF1 pathway	1291	32	8.32	3.85	9.79e-11	8.13e-10	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1648	Class I PI3K signaling events mediated by Akt	1288	32	8.30	3.85	9.24e-11	8.13e-10	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1603	EGFR-dependent Endothelin signaling events	1289	32	8.31	3.85	9.42e-11	8.13e-10	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1454	Syndecan-1-mediated signaling events	1300	32	8.38	3.82	1.17e-10	8.13e-10	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1635	Sphingosine 1-phosphate (S1P) pathway	1311	32	8.45	3.79	1.44e-10	9.69e-10	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1573	ErbB receptor signaling network	1312	32	8.46	3.78	1.47e-10	9.69e-10	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1480	TRAIL signaling pathway	1328	32	8.56	3.74	1.98e-10	1.27e-09	ID ASD
MAPK8 \| RB1CC1 \| HSPA8 \| SMAD7 \| LRP1 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| BCAT1 \| SMARCC2 \| NUP214 \| BLNK \| ICAM1 \| KPNA1 \| ASAP2 \| TRRAP \| EPHA2 \| HIF1A \| ASAP1 \| HUWE1 \| CHD8 \| GNAO1 \| PYCARD \| PML \| ACTA2 \| PTK2B \| SERPINI1 \| HSP90AA1 \| ITSN1 \| NOS3
DB_ID:1546	Integrin-linked kinase signaling	656	19	4.23	4.49	6.92e-08	4.34e-07	ID ASD
MAPK8 \| HSPA8 \| SMAD7 \| CUL3 \| CAMK4 \| RUNX3 \| ACTN1 \| SMARCC2 \| NUP214 \| ICAM1 \| TRRAP \| HIF1A \| CHD8 \| PML \| ZEB1 \| PTK2B \| HSP90AA1 \| ADCY7
DB_ID:1565	AP-1 transcription factor network	623	17	4.02	4.23	7.80e-07	4.77e-06	ID ASD
MAPK8 \| HSPA8 \| SMAD7 \| CUL3 \| CAMK4 \| RUNX3 \| SMARCC2 \| NUP214 \| ICAM1 \| TRRAP \| CHD8 \| HIF1A \| PML \| PTK2B \| HSP90AA1 \| ADCY7
DB_ID:1456	Regulation of CDC42 activity	770	18	4.96	3.63	3.27e-06	1.95e-05	ID ASD
MAPK8 \| HSPA8 \| SMAD7 \| CUL3 \| CAMK4 \| RUNX3 \| SMARCC2 \| NUP214 \| ICAM1 \| TRRAP \| CHD8 \| HIF1A \| PML \| PTK2B \| HSP90AA1 \| ITSN1 \| ADCY7
DB_ID:1488	CDC42 signaling events	757	17	4.88	3.48	1.03e-05	6.02e-05	ID ASD
MAPK8 \| HSPA8 \| SMAD7 \| CUL3 \| CAMK4 \| RUNX3 \| SMARCC2 \| NUP214 \| ICAM1 \| TRRAP \| CHD8 \| HIF1A \| PML \| PTK2B \| HSP90AA1 \| ADCY7
DB_ID:20	Axon guidance	219	9	1.41	6.38	1.41e-05	8.05e-05	ID ASD
SLIT3 \| MYH9 \| NCAN \| NFASC \| HSP90AA1 \| MYH10 \| SLIT2 \| CACNA1I
DB_ID:1471	Glypican 3 network	206	8	1.33	6.02	6.29e-05	0.0003	ID ASD
MAPK8 \| TRRAP \| CHD8 \| CUL3 \| PTK2B \| CAMK4 \| LRP5
DB_ID:1435	Wnt signaling network	200	8	1.29	6.21	5.11e-05	0.0003	ID ASD
MAPK8 \| TRRAP \| CHD8 \| CUL3 \| PTK2B \| CAMK4 \| LRP5
DB_ID:1604	Syndecan-4-mediated signaling events	209	8	1.35	5.94	6.96e-05	0.0004	ID ASD
MAPK8 \| TRRAP \| CHD8 \| CUL3 \| PTK2B \| CAMK4 \| ACTN1
DB_ID:488	G-protein mediated events	40	4	0.26	15.51	0.0001	0.0005	-
CAMK4 \| GNAO1 \| ADCY9
DB_ID:487	PLC beta mediated events	39	4	0.25	15.91	0.0001	0.0005	-
CAMK4 \| GNAO1 \| ADCY9
DB_ID:150	Transmission across Chemical Synapses	121	6	0.78	7.69	0.0001	0.0005	ID ASD EE
CAMK4 \| GRIN2A \| GNB2 \| HSPA8 \| ADCY9
DB_ID:1451	Signaling events mediated by HDAC Class I	113	6	0.73	8.24	9.64e-05	0.0005	-
CAMK4 \| HIST1H1E \| CHD4 \| HSP90AA1 \| NUP214
DB_ID:143	Neuronal System	188	7	1.21	5.78	0.0002	0.0009	ID ASD EE
CAMK4 \| GRIN2A \| KCNH6 \| GNB2 \| HSPA8 \| ADCY9
DB_ID:1493	Validated targets of C-MYC transcriptional activation	81	5	0.52	9.58	0.0002	0.0009	ID ASD
SERPINI1 \| BCAT1 \| HSP90AA1 \| TRRAP
DB_ID:1535	Noncanonical Wnt signaling pathway	182	7	1.17	5.97	0.0002	0.0009	ID ASD
CAMK4 \| PTK2B \| MAPK8 \| TRRAP \| CHD8 \| CUL3
DB_ID:1494	N-cadherin signaling events	251	8	1.62	4.94	0.0002	0.0009	ID ASD
CAMK4 \| PTK2B \| MAPK8 \| LRP5 \| TRRAP \| DAGLB \| CHD8
DB_ID:130	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell	89	5	0.57	8.72	0.0003	0.0014	ID ASD EE
CAMK4 \| GRIN2A \| GNB2 \| ADCY9
DB_ID:486	Opioid Signalling	53	4	0.34	11.71	0.0004	0.0017	-
CAMK4 \| GNAO1 \| ADCY9
DB_ID:1467	C-MYC pathway	149	6	0.96	6.25	0.0004	0.0017	ASD
SERPINI1 \| BCAT1 \| HSP90AA1 \| TRRAP \| HUWE1
DB_ID:18	Sema4D induced cell migration and growth-cone collapse	22	3	0.14	21.15	0.0004	0.0017	ASD
MYH9 \| MYH10
DB_ID:339	CaM pathway	25	3	0.16	18.62	0.0005	0.0020	ASD
CAMK4 \| ADCY9
DB_ID:1542	Canonical Wnt signaling pathway	155	6	1.00	6.01	0.0005	0.0020	ID ASD
CAMK4 \| PTK2B \| TRRAP \| CHD8 \| CUL3
DB_ID:338	Calmodulin induced events	25	3	0.16	18.62	0.0005	0.0020	ASD
CAMK4 \| ADCY9
DB_ID:1481	LPA receptor mediated events	100	5	0.64	7.76	0.0005	0.0020	-
PTK2B \| GNAO1 \| LPAR3 \| ADCY9
DB_ID:11	Developmental Biology	433	10	2.79	3.58	0.0006	0.0024	ID ASD
SLIT3 \| MYH9 \| NCAN \| NFASC \| HSP90AA1 \| MYH10 \| CACNA1I \| SLIT2 \| CTNNA2
DB_ID:16	Sema4D in semaphorin signaling	27	3	0.17	17.24	0.0007	0.0026	ASD
MYH9 \| MYH10
DB_ID:323	Phospholipase C-mediated cascade	27	3	0.17	17.24	0.0007	0.0026	ASD
CAMK4 \| ADCY9
DB_ID:493	Ca-dependent events	27	3	0.17	17.24	0.0007	0.0026	ASD
CAMK4 \| ADCY9
DB_ID:522	Immune System	532	11	3.43	3.21	0.0007	0.0026	ID ASD
MAPK8 \| PSMD2 \| TLR7 \| PYCARD \| NLRC5 \| PML \| ATG12 \| PTK2B \| CD14 \| BLNK
DB_ID:336	DAG and IP3 signaling	27	3	0.17	17.24	0.0007	0.0026	ASD
CAMK4 \| ADCY9
DB_ID:183	Activation of GABAB receptors	28	3	0.18	16.62	0.0008	0.0028	-
GNB2 \| ADCY9
DB_ID:186	GABA B receptor activation	28	3	0.18	16.62	0.0008	0.0028	-
GNB2 \| ADCY9
DB_ID:21	Semaphorin interactions	64	4	0.41	9.70	0.0008	0.0028	ASD
MYH9 \| HSP90AA1 \| MYH10
DB_ID:1539	VEGFR1 specific signals	29	3	0.19	16.05	0.0009	0.0030	-
HSP90AA1 \| HIF1A
DB_ID:1523	Reelin signaling pathway	29	3	0.19	16.05	0.0009	0.0030	ID ASD
MAPK8 \| RELN
DB_ID:754	Transport of Ribonucleoproteins into the Host Nucleus	29	3	0.19	16.05	0.0009	0.0030	-
TPR \| KPNA1
DB_ID:240	PLC-gamma1 signalling	30	3	0.19	15.51	0.0009	0.0030	ASD
CAMK4 \| ADCY9
DB_ID:337	EGFR interacts with phospholipase C-gamma	29	3	0.19	16.05	0.0009	0.0030	ASD
CAMK4 \| ADCY9
DB_ID:198	Vpr-mediated nuclear import of PICs	31	3	0.20	15.01	0.0010	0.0033	-
TPR \| KPNA1
DB_ID:846	Glucagon signaling in metabolic regulation	33	3	0.21	14.10	0.0013	0.0041	ASD
GNB2 \| ADCY9
DB_ID:1662	TGFBR	125	5	0.81	6.21	0.0013	0.0041	ID
ZEB1 \| MAPK8 \| NUP214 \| HSPA8
DB_ID:643	eNOS activation	9	2	0.06	34.47	0.0014	0.0043	-
HSP90AA1
DB_ID:200	Interactions of Vpr with host cellular proteins	34	3	0.22	13.69	0.0014	0.0043	-
TPR \| KPNA1
DB_ID:1601	p53 pathway	189	6	1.22	4.92	0.0015	0.0045	-
MAPK8 \| TRRAP \| EPHA2 \| HUWE1 \| PYCARD
DB_ID:1094	Innate Immune System	190	6	1.22	4.90	0.0015	0.0045	-
ATG12 \| MAPK8 \| TLR7 \| CD14 \| PYCARD
DB_ID:1593	CXCR4-mediated signaling events	192	6	1.24	4.85	0.0016	0.0047	EE
PTK2B \| RASSF5 \| MAPK8 \| GNAO1 \| UBQLN1
DB_ID:192	GABA receptor activation	36	3	0.23	12.93	0.0016	0.0047	ASD EE
GNB2 \| ADCY9
DB_ID:1577	Glucocorticoid receptor regulatory network	80	4	0.52	7.76	0.0018	0.0052	-
MAPK8 \| HSP90AA1 \| SMARCC2
DB_ID:494	Adenylate cyclase activating pathway	10	2	0.06	31.03	0.0018	0.0052	-
ADCY9
DB_ID:1547	Regulation of nuclear beta catenin signaling and target gene transcription	135	5	0.87	5.75	0.0019	0.0054	ID ASD
CAMK4 \| PTK2B \| TRRAP \| CHD8
DB_ID:1468	Signaling events mediated by HDAC Class II	38	3	0.24	12.25	0.0019	0.0054	-
CAMK4 \| HSP90AA1
DB_ID:1469	Stabilization and expansion of the E-cadherin adherens junction	275	7	1.77	3.95	0.0022	0.0061	ID ASD
CAMK4 \| PTK2B \| ACTN1 \| TRRAP \| EPHA2 \| CHD8
DB_ID:1544	E-cadherin signaling in the nascent adherens junction	275	7	1.77	3.95	0.0022	0.0061	ID ASD
CAMK4 \| PTK2B \| ACTN1 \| TRRAP \| EPHA2 \| CHD8
DB_ID:1569	Glucocorticoid receptor signaling	85	4	0.55	7.30	0.0023	0.0063	ASD
MAPK8 \| HSP90AA1 \| SMARCC2
DB_ID:1617	E-cadherin signaling events	280	7	1.80	3.88	0.0024	0.0065	ID ASD
CAMK4 \| PTK2B \| ACTN1 \| TRRAP \| EPHA2 \| CHD8
DB_ID:636	Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation	12	2	0.08	25.86	0.0026	0.0070	-
HSP90AA1
DB_ID:905	Metabolism of carbohydrates	92	4	0.59	6.74	0.0030	0.0079	-
TPR \| LCT \| NUP214
DB_ID:182	Inhibition of adenylate cyclase pathway	13	2	0.08	23.87	0.0031	0.0080	-
ADCY9
DB_ID:185	Adenylate cyclase inhibitory pathway	13	2	0.08	23.87	0.0031	0.0080	-
ADCY9
DB_ID:756	Meiotic Synapsis	47	3	0.30	9.90	0.0035	0.0090	ID
SYNE1 \| STAG1
DB_ID:1611	Regulation of nuclear SMAD2/3 signaling	305	7	1.97	3.56	0.0038	0.0095	ASD
CAMK4 \| MAPK8 \| RUNX3 \| NUP214 \| HSPA8 \| PML
DB_ID:1510	TGF-beta receptor signaling	305	7	1.97	3.56	0.0038	0.0095	ASD
CAMK4 \| MAPK8 \| RUNX3 \| NUP214 \| HSPA8 \| PML
DB_ID:1440	Regulation of cytoplasmic and nuclear SMAD2/3 signaling	305	7	1.97	3.56	0.0038	0.0095	ASD
CAMK4 \| MAPK8 \| RUNX3 \| NUP214 \| HSPA8 \| PML
DB_ID:1614	Angiopoietin receptor Tie2-mediated signaling	50	3	0.32	9.31	0.0042	0.0103	-
TEK \| MAPK8
DB_ID:146	Muscle contraction	50	3	0.32	9.31	0.0042	0.0103	-
ACTA2 \| NEB
DB_ID:1438	LPA4-mediated signaling events	16	2	0.10	19.39	0.0047	0.0114	ASD
ADCY9
DB_ID:1612	ALK1 signaling events	321	7	2.07	3.38	0.0051	0.0122	ASD
CAMK4 \| MAPK8 \| RUNX3 \| NUP214 \| HSPA8 \| PML
DB_ID:847	PKA activation in glucagon signalling	17	2	0.11	18.25	0.0053	0.0124	ASD
ADCY9
DB_ID:1518	Thromboxane A2 receptor signaling	54	3	0.35	8.62	0.0052	0.0124	-
TGM2 \| ICAM1
DB_ID:1583	ALK1 pathway	324	7	2.09	3.35	0.0053	0.0124	ASD
CAMK4 \| MAPK8 \| RUNX3 \| NUP214 \| HSPA8 \| PML
DB_ID:1609	ATR signaling pathway	250	6	1.61	3.72	0.0059	0.0133	-
MAPK8 \| TRRAP \| EPHA2 \| HUWE1 \| PYCARD
DB_ID:641	Metabolism of nitric oxide	18	2	0.12	17.24	0.0059	0.0133	-
HSP90AA1
DB_ID:917	Fatty Acyl-CoA Biosynthesis	18	2	0.12	17.24	0.0059	0.0133	-
ACSL4
DB_ID:640	eNOS activation and regulation	18	2	0.12	17.24	0.0059	0.0133	-
HSP90AA1
DB_ID:1665	NOTCH	57	3	0.37	8.16	0.0060	0.0134	ASD
HIVEP3 \| DLL4
DB_ID:332	PKA activation	19	2	0.12	16.33	0.0066	0.0146	-
ADCY9
DB_ID:570	Cholesterol biosynthesis	20	2	0.13	15.51	0.0073	0.0159	-
SQLE
DB_ID:333	PKA-mediated phosphorylation of CREB	20	2	0.13	15.51	0.0073	0.0159	-
ADCY9
DB_ID:634	Metabolism	824	12	5.31	2.26	0.0077	0.0166	ASD
FLAD1 \| TPR \| PSMD2 \| HSPA8 \| ADCY9 \| BCAT1 \| HSP90AA1 \| DPYD \| NUP214 \| GNB2 \| NOS3
DB_ID:1453	Integrins in angiogenesis	64	3	0.41	7.27	0.0083	0.0178	-
PTK2B \| MAPK8
DB_ID:484	G alpha (z) signalling events	22	2	0.14	14.10	0.0088	0.0187	ASD
ADCY9
DB_ID:325	Downstream signaling of activated FGFR	66	3	0.43	7.05	0.0090	0.0190	ASD
CAMK4 \| ADCY9
DB_ID:116	NCAM1 interactions	23	2	0.15	13.49	0.0096	0.0201	ASD
NCAN
DB_ID:144	Smooth Muscle Contraction	24	2	0.15	12.93	0.0104	0.0210	-
ACTA2
DB_ID:981	Regulation of Water Balance by Renal Aquaporins	24	2	0.15	12.93	0.0104	0.0210	ASD
ADCY9
DB_ID:520	Cytosolic tRNA aminoacylation	24	2	0.15	12.93	0.0104	0.0210	-
YARS
DB_ID:1618	Androgen-mediated signaling	130	4	0.84	4.77	0.0102	0.0210	ID
PTK2B \| MAPK8 \| HSP90AA1
DB_ID:239	HIV Infection	204	5	1.31	3.80	0.0107	0.0215	-
TPR \| PSMD2 \| TAF13 \| KPNA1
DB_ID:758	Meiosis	72	3	0.46	6.46	0.0114	0.0225	ID
SYNE1 \| STAG1
DB_ID:1274	superpathway of cholesterol biosynthesis	25	2	0.16	12.41	0.0113	0.0225	-
SQLE
DB_ID:749	Influenza Life Cycle	136	4	0.88	4.56	0.0119	0.0233	-
TPR \| KPNA1 \| HSP90AA1
DB_ID:1504	S1P2 pathway	26	2	0.17	11.93	0.0122	0.0238	-
MAPK8
DB_ID:1629	Direct p53 effectors	138	4	0.89	4.50	0.0125	0.0240	-
TRRAP \| EPHA2 \| PYCARD
DB_ID:1664	EGFR1	138	4	0.89	4.50	0.0125	0.0240	ASD
PTK2B \| MAPK8 \| PIK3C2B
DB_ID:467	Downstream signal transduction	75	3	0.48	6.21	0.0127	0.0242	ASD
CAMK4 \| ADCY9
DB_ID:992	Aquaporin-mediated transport	27	2	0.17	11.49	0.0131	0.0248	ASD
ADCY9
DB_ID:755	Influenza Infection	141	4	0.91	4.40	0.0134	0.0251	-
TPR \| KPNA1 \| HSP90AA1
DB_ID:254	Signalling by NGF	143	4	0.92	4.34	0.0140	0.0255	ASD
CAMK4 \| MAPK8 \| ADCY9
DB_ID:1121	Negative regulators of RIG-I/MDA5 signaling	28	2	0.18	11.08	0.0140	0.0255	-
ATG12
DB_ID:201	Host Interactions of HIV factors	142	4	0.92	4.37	0.0137	0.0255	-
TPR \| PSMD2 \| KPNA1
DB_ID:466	Signaling by PDGF	78	3	0.50	5.97	0.0141	0.0255	ASD
CAMK4 \| ADCY9
DB_ID:920	Triglyceride Biosynthesis	28	2	0.18	11.08	0.0140	0.0255	-
ACSL4
DB_ID:740	NEP/NS2 Interacts with the Cellular Export Machinery	29	2	0.19	10.70	0.0150	0.0266	-
TPR
DB_ID:901	Regulation of Glucokinase by Glucokinase Regulatory Protein	29	2	0.19	10.70	0.0150	0.0266	-
TPR
DB_ID:1599	ATM pathway	307	6	1.98	3.03	0.0151	0.0266	ID
MAPK8 \| TRRAP \| EPHA2 \| HUWE1 \| PYCARD
DB_ID:1439	Osteopontin-mediated events	29	2	0.19	10.70	0.0150	0.0266	-
PTK2B
DB_ID:1657	Wnt	82	3	0.53	5.68	0.0161	0.0280	ID
MAPK8 \| LRP5
DB_ID:4	Nuclear import of Rev protein	30	2	0.19	10.34	0.0160	0.0280	-
TPR
DB_ID:812	Integration of energy metabolism	83	3	0.54	5.61	0.0167	0.0288	ASD
GNB2 \| ADCY9
DB_ID:742	Export of Viral Ribonucleoproteins from Nucleus	31	2	0.20	10.01	0.0170	0.0289	-
TPR
DB_ID:476	G alpha (s) signalling events	31	2	0.20	10.01	0.0170	0.0289	ASD
ADCY9
DB_ID:1512	Posttranslational regulation of adherens junction stability and dissassembly	231	5	1.49	3.36	0.0174	0.0294	ID ASD
CAMK4 \| PTK2B \| TRRAP \| CHD8
DB_ID:203	Rev-mediated nuclear export of HIV-1 RNA	32	2	0.21	9.70	0.0181	0.0300	-
TPR
DB_ID:387	Transport of the SLBP independent Mature mRNA	32	2	0.21	9.70	0.0181	0.0300	-
TPR
DB_ID:475	G alpha (i) signalling events	32	2	0.21	9.70	0.0181	0.0300	ASD
ADCY9
DB_ID:1537	Alpha4 beta1 integrin signaling events	33	2	0.21	9.40	0.0192	0.0312	-
PTK2B
DB_ID:392	Transport of the SLBP Dependant Mature mRNA	33	2	0.21	9.40	0.0192	0.0312	-
TPR
DB_ID:5	Interactions of Rev with host cellular proteins	33	2	0.21	9.40	0.0192	0.0312	-
TPR
DB_ID:140	Activation of NMDA receptor upon glutamate binding and postsynaptic events	34	2	0.22	9.13	0.0203	0.0326	ID ASD
CAMK4
DB_ID:142	Post NMDA receptor activation events	34	2	0.22	9.13	0.0203	0.0326	ID ASD
CAMK4
DB_ID:1095	Toll Receptor Cascades	90	3	0.58	5.17	0.0206	0.0329	-
MAPK8 \| TLR7
DB_ID:386	Transport of Mature mRNA Derived from an Intronless Transcript	35	2	0.23	8.86	0.0214	0.0339	-
TPR
DB_ID:219	Late Phase of HIV Life Cycle	92	3	0.59	5.06	0.0218	0.0344	-
TPR \| TAF13
DB_ID:393	Transport of Mature mRNAs Derived from Intronless Transcripts	36	2	0.23	8.62	0.0226	0.0354	-
TPR
DB_ID:1457	Notch-mediated HES/HEY network	94	3	0.61	4.95	0.0231	0.0358	ID ASD
DLL4 \| HIF1A
DB_ID:1625	Notch signaling pathway	94	3	0.61	4.95	0.0231	0.0358	ID ASD
DLL4 \| HIF1A
DB_ID:306	Signaling by FGFR	95	3	0.61	4.90	0.0237	0.0363	ASD
CAMK4 \| ADCY9
DB_ID:1587	Role of Calcineurin-dependent NFAT signaling in lymphocytes	95	3	0.61	4.90	0.0237	0.0363	-
CAMK4 \| MAPK8
DB_ID:900	Glucose transport	38	2	0.24	8.16	0.0250	0.0380	-
TPR
DB_ID:330	Signaling by EGFR	98	3	0.63	4.75	0.0257	0.0389	ASD
CAMK4 \| ADCY9
DB_ID:903	Hexose transport	40	2	0.26	7.76	0.0275	0.0413	-
TPR
DB_ID:1568	amb2 Integrin signaling	41	2	0.26	7.57	0.0288	0.0430	-
ICAM1
DB_ID:229	HIV Life Cycle	103	3	0.66	4.52	0.0292	0.0434	-
TPR \| TAF13
DB_ID:858	Regulation of mRNA Stability by Proteins that Bind AU-rich Elements	104	3	0.67	4.47	0.0300	0.0442	-
PSMD2 \| NUP214
DB_ID:519	tRNA Aminoacylation	42	2	0.27	7.39	0.0301	0.0442	-
YARS
DB_ID:289	NGF signalling via TRKA from the plasma membrane	107	3	0.69	4.35	0.0322	0.0470	ASD
CAMK4 \| ADCY9
DB_ID:1636	Regulation of Androgen receptor activity	108	3	0.70	4.31	0.0330	0.0479	ID
PTK2B \| MAPK8
DB_ID:111	Netrin-1 signaling	45	2	0.29	6.89	0.0342	0.0494	-
SLIT3 \| SLIT2