for non-coding RNA discovery, profiling and functional annotation based on high-throughput sequencing
mirTools2.0 - for non-coding RNA discovery, profiling and functional annotation based on high-throughput sequencing
Welcome to mirTools 2.0 Old version

Non-coding RNAs (ncRNAs), such as miRNAs, tRNA, snRNA, snoRNA are involved in numerous important biological processes. The next generation sequencing technologies have been applied in prediction and profiling of the microRNAs. During the past two years, our comprehensive web server, mirTools 1.0, has been wildly used by public researchers and provided detailed annotation of microRNAs. Here we developed the web service, mirTools 2.0, the updated version of mirTools, which includes the following new features:

 

1) From just microRNA discovery in mirTools 1.0 to allow users to detect and profile the non-coding RNAs, including tRNA, snRNA, snoRNA, rRNAs and piRNAs.

 

2) From just microRNA profiling in mirTools 1.0 to allow users to identify the microRNA targeted genes and detailed functional annotate of microRNA targets genes, including Gene Ontology, KEGG pathway and protein protein interaction.

 

3) From just comparison of two RNA-seq samples for differentially expressed microRNAs in mirTools 1.0 to allow users to perform the comparison of many samples and identify the differentially expressed non-coding RNAs between experimental groups.

 

4) Other significant improvement in comparison with mirTools 1.0: improved method used to detect novel microRNAs, allow users to detect novel piRNAs, allow users to detect more know microRNAs in more kind of taxonomy, less computational time etc.

Breaking news

The stand-alone software version of mirTools 2.0 was released

May. 11, 2013
The stand-alone software version of mirTools 2.0 was released, which contains the whole pipeline of mirTools 2.0. The stand-alone ...

[More]

The bugs in plant ncRNAs analysis were corrected

Apr. 16, 2013
Two bugs in plant ncRNAs analysis were corrected.Additionally, we also carefully checked
...

[More]

mirTools 2.0 has been released

Dec. 16, 2012
mirTools 2.0 is released to allow users to perform non-coding RNAs profiling, miRNAs targets predition, function annotaion of targets ...
[More]
Pipeline of mirTools 2.0

Institute of Genomic Medicine, Wenzhou Medical College
Wenzhou 325035, Zhejiang, China